Two New Compounds from the Deep-Sea-Derived Fungus Aspergillus sp. YPGA8

被引:2
作者
Pan, Meng-Hua [1 ]
Tian, Zhi-Yong [1 ]
Yang, Hui [1 ]
Xu, Wei [2 ]
Pan, Chen [1 ]
Cheng, Zhong-Bin [1 ,3 ]
Li, Qin [1 ,3 ]
机构
[1] Henan Univ, Sch Pharm, Kaifeng 475004, Henan, Peoples R China
[2] Minist Nat Resources, Key Lab Marine Biogenet Resources, Inst Oceanog 3, Xiamen 361005, Peoples R China
[3] Eucommia Ulmoides Cultivat & Utilizat Henan Engn, Kaifeng 475004, Peoples R China
基金
中国博士后科学基金; 国家重点研发计划;
关键词
Aspergillus sp; aspertriols A-B; isolation; identification; DERIVATIVES;
D O I
10.25135/rnp.162.19.11.1487
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Chemical examination of a fraction of the EtOAc extract of a marine-derived fungus Aspergillus sp. YPGA8 resulted in the isolation of two new compounds, namely aspertriols A-B (1-2). Compounds 1-2 possess an identical 2,3,4-trihydroxybutoxy moiety, which is rarely found in natural products. Their structures were determined by extensive analyses of spectroscopic data (1D and 2D NMR, HRESIMS). The bioassay study revealed that compounds 1 and 2 were inactive toward alpha-glucosidase.
引用
收藏
页码:307 / 311
页数:5
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