Mechanisms of pathogenesis: evasion of killing by polymorphonuclear leukocytes

被引:46
|
作者
Allen, LAH
机构
[1] Univ Iowa, Dept Med, Iowa City, IA 52241 USA
[2] Univ Iowa, Inflammat Program, Iowa City, IA 52241 USA
[3] Vet Adm Med Ctr, Iowa City, IA 52241 USA
关键词
phagocytosis; NADPH oxidase; phagosome maturation; macrophage; neutrophil;
D O I
10.1016/j.micinf.2003.09.011
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Few microorganisms evade killing by neutrophils. Summarized here are the mechanisms used by Yersinia, group A streptococci, Helicobacter Ehrlichia and Francisella to block phagocytosis, disrupt phagosome maturation or perturb the respiratory burst. Also discussed are mechanisms used by neutrophils to control organisms that replicate inside macrophages. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:1329 / 1335
页数:7
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