Blood transfusion at delivery and risk of subsequent malignant lymphoma in the mother

被引:11
作者
Anderson, H [1 ]
Brandt, L
Ericson, A
Olsson, H
Möller, T
机构
[1] Univ Lund Hosp, So Swedish Reg Tumour Registry, S-22185 Lund, Sweden
[2] Univ Lund Hosp, Dept Oncol, S-22185 Lund, Sweden
[3] Natl Board Hlth & Welf, Ctr Epidemiol, Stockholm, Sweden
关键词
D O I
10.1046/j.1423-0410.1998.7520145.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and Objectives: Blood transfusion has been shown to be a risk factor for non-Hodgkin's lymphoma (NHL). Materials and Methods: In a cohort of 77,928 women with bleeding complications at delivery in the period of 1973-1986, subsequent NHL cases were identified and the number was compared with the number expected from national incidence rates. In a case-control study the proportion of transfused NHL cases was compared with the proportion of transfused controls. Results: The observed number of NHL in the cohort was 18 versus 22.0 expected. Information on transfusion was obtained for 15 of the NHL cases and none (0%) was transfused versus 32 out of 136 controls (23%), Conclusions: Blood transfusion at delivery is not a risk factor for NHL. The immune tolerance induced by pregnancy may reduce the risk of NHL associated with the transfusion of allogeneic blood cells.
引用
收藏
页码:145 / 148
页数:4
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