Regulation of Wnt gene expression

被引：2

作者：

Tian, Q

Jin, H

Cui, YZ

Guo, CS

Lu, X

机构：

[1] Oregon Hlth & Sci Univ, Sch Med, Dept Pathol, Portland, OR 97239 USA

[2] Oregon Coll Oriental Med, Portland, OR 97216 USA

[3] Oregon Hlth & Sci Univ, OGI Sch Sci & Engn, Dept Environm & Biochem Sci, Beaverton, OR 97006 USA

[4] Shriners Hosp Children, Portland Unit, Portland, OR 97201 USA

[5] Nanjing Med Univ, Jiangsu Prov Hosp, Dept Cardiol, Nanjing 210029, Peoples R China

来源：

DEVELOPMENT GROWTH & DIFFERENTIATION | 2005年 / 47卷 / 05期

关键词：

gene expression; post-transcription; transcription; translation; Wnt;

D O I：

暂无

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Members of the Wnt gene family play important roles in the regulation of a number of basic developmental processes. Because Wnt is such a potent morphogen, its expression must be controlled tightly and precisely. While many review papers focused on Wnt signaling downstream of the receptor, this review addresses regulations of Wnt itself on several levels, including the transcriptional level, RNA splicing, the post-transcriptional level, the translational level, and the post-translational level. It is these multiple, precise and tight regulations that guarantee that Wnts function correctly both temporally and spatially.

引用

收藏

页码：273 / 281

页数：9

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