THE INNATE-LIKE BYSTANDER-ACTIVATED CD38+HLADR+CD8+T CELLS PLAY A PATHOGENIC ROLE IN THE LIVER INJURY AND PROGRESSION OF FIBROSIS IN PATIENTS WITH CHRONIC HEPATITIS C

被引：0
|
作者：
Huang, Chien-Hao [1 ,2 ]
Fan, Jian He [2 ]
Jeng, Wen-Juei [2 ,3 ,4 ,5 ]
Chang, Shu-Ting [6 ]
Yang, Chan-Keng [7 ]
Wu, Tsung-Han [8 ]
Hsieh, Yi-Chung [9 ]
Teng, Wei [6 ,10 ,11 ]
Chen, Yicheng [6 ]
Chen, Wei-Ting [6 ]
Sheen, I-Shyan [11 ]
Lin, Yung-Chang [1 ,7 ]
Lin, Chun-Yen [12 ]
机构：
[1] Chang Gung Mem Hosp, Linkou Med Ctr, Taoyuan, Taiwan
[2] Chang Gung Mem Hosp, Linkou Med Ctr, Dept Gastroenterol & Hepatol, Taoyuan, Taiwan
[3] Chang Gung Mem Hosp, Linkou Branch, Dept Gastroenterol & Hepatol, Taoyuan, Taiwan
[4] Chang Gung Univ, Coll Med, Taoyuan, Taiwan
[5] Natl Yang Ming Univ, Inst Clin Med, Taipei, Taiwan
[6] Chang Gung Mem Hosp, Linkou Med Ctr, Taoyuan, Taiwan
[7] Chang Gung Mem Hosp, Div Med Oncol Hematol, Taoyuan, Taiwan
[8] Chang Gung Mem Hosp, Linkou Med Ctr, Div Gen Surg, Taoyuan, Taiwan
[9] Linkou Chang Gung Mem Hosp, Taoyuan, Taiwan
[10] Chang Gung Univ, Coll Med, Taoyuan, Taiwan
[11] Chang Gung Mem Hosp, Linkou Branch, Gastroenterol & Hepatol, Taoyuan, Taiwan
[12] Chang Gung Mem Hosp, Dept Gastroenterol & Hepatol, Linkou, Taiwan
来源：
HEPATOLOGY | 2021年 / 74卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
1002
引用
收藏
页码：612A / 613A
页数：2
相关论文
共 14 条
  • [1] Innate-like bystander-activated CD38+HLA-DR+CD8+T cells play a pathogenic role in patients with chronic hepatitis C
    Huang, Chien-Hao
    Fan, Jian-He
    Jeng, Wen-Juei
    Chang, Shu-Ting
    Yang, Chan-Keng
    Teng, Wei
    Wu, Tsung-Han
    Hsieh, Yi-Chung
    Chen, Wei-Ting
    Chen, Yi-Cheng
    Sheen, I-Shyan
    Lin, Yung-Chang
    Lin, Chun-Yen
    HEPATOLOGY, 2022, 76 (03) : 803 - 818
  • [2] Innate-like Cytotoxic Function of Bystander-Activated CD8+ T Cells Is Associated with Liver Injury in Acute Hepatitis A
    Kim, Jihye
    Chang, Dong-Yeop
    Lee, Hyun Woong
    Lee, Hoyoung
    Kim, Jong Hoon
    Sung, Pil Soo
    Kim, Kyung Hwan
    Hong, Seon-Hui
    Kang, Wonseok
    Lee, Jino
    Shin, So Youn
    Yu, Hee Tae
    You, Sooseong
    Choi, Yoon Seok
    Oh, Insoo
    Lee, Dong Ho
    Lee, Dong Hyeon
    Jung, Min Kyung
    Suh, Kyung-Suk
    Hwang, Shin
    Kim, Won
    Park, Su-Hyung
    Kim, Hyung Joon
    Shin, Eui-Cheol
    IMMUNITY, 2018, 48 (01) : 161 - +
  • [3] Memory CD8 T cells that are bystander-activated during an infection control early pathogen replication in an innate-like manner
    Prlic, Martin
    Chu, Talyn
    JOURNAL OF IMMUNOLOGY, 2013, 190
  • [4] Bystander-Activated Memory CD8 T Cells Control Early Pathogen Load in an Innate-like, NKG2D-Dependent Manner
    Chu, Talyn
    Tyznik, Aaron J.
    Roepke, Sarah
    Berkley, Amy M.
    Woodward-Davis, Amanda
    Pattacini, Laura
    Bevan, Michael J.
    Zehn, Dietmar
    Prlic, Martin
    CELL REPORTS, 2013, 3 (03): : 701 - 708
  • [5] Interleukin-1 and IL-23 induce innate-like immune responses by bystander-activated memory CD4+ T cells contributing to the autoimmune pathogenesis
    Lee, Hong-Gyun
    Lee, Jae-Ung
    Kang, Insoo
    Choi, Je-Min
    JOURNAL OF IMMUNOLOGY, 2018, 200 (01):
  • [6] EOMESODERMIN-EXPRESSING INNATE-LIKE CD8+T CELLS IN HUMANS ARE IMPAIRED IN CHRONIC MYELOID LEUKEMIA PATIENTS AT DIAGNOSIS
    Herbelin, Andre
    Jacomet, Florence
    Cayssals, Emilie
    Desmier, Deborah
    Barbarin, Alice
    Basbous, Sara
    Levescot, Anais
    Robin, Aurelie
    Giraud, Christine
    Barra, Anne
    Guilhot, Francois
    Roy, Lydia
    Gombert, Jean-Marc
    JOURNAL OF IMMUNOLOGY, 2016, 196
  • [7] THE IMPACT OF PD-1+ INNATE-LIKE CD8+T CELLS ON THE HBSAG REDUCTION IN ACTIVE CHRONIC HEPATITIS B PATIENTS RECEIVING NUCLEOS(T) IDE ANALOGUE THERAPY
    Jeng, Rachel Wen-Juei
    Huang, Hsiang-Wei
    Lin, Chia-Wei
    Fan, Jian He
    Liu, Yen-Chun
    Ku, Wei-Ting
    Wu, Cheng-Heng
    Huang, Chien-Hao
    Lin, Yung-Chang
    Lin, Chun Yen
    HEPATOLOGY, 2024, 80 : S755 - S756
  • [8] Hepatitis C virus specific CD8+T cells compartimentalize to the liver and are associated with low fibrosis stage in chronic C hepatitis.
    Ziol, M
    Bonilla, N
    Barget, N
    Roulot, D
    Andrieu, M
    Grando, V
    Trinchet, JC
    Ganne-Carrié, N
    Beaugrand, M
    Guillet, JG
    HEPATOLOGY, 2002, 36 (04) : 277A - 277A
  • [9] Distinct CD4+CD8+ Double-Positive T Cells in the Blood and Liver of Patients during Chronic Hepatitis B and C
    Nascimbeni, Michelina
    Pol, Stanislas
    Saunier, Bertrand
    PLOS ONE, 2011, 6 (05):
  • [10] IL-15-activated bystander CD8+ T cells contribute to host injury by NK-like cytolytic activity in acute viral hepatitis
    Chang, Dong-Yeop
    Lee, Hyun Woong
    Kang, Wonseok
    Cheon, Doo-Sung
    Kim, Hyung Joon
    Shin, Eui-Cheol
    JOURNAL OF IMMUNOLOGY, 2012, 188
12