Defined High Molar Mass Poly(2-Oxazoline)s

被引：74

作者：

Monnery, Bryn D. ^{[1
]}

Jerca, Valentin V. ^{[1
,2
]}

Sedlacek, Ondrej ^{[1
]}

Verbraeken, Bart ^{[1
]}

Cavill, Rachel ^{[3
]}

Hoogenboom, Richard ^{[1
]}

机构：

[1] Univ Ghent, Dept Organ & Macromol Chem, Ctr Macromol Chem, Supramol Chem Grp, Krijgslaan 281-S4, B-9000 Ghent, Belgium

[2] Romanian Acad, Ctr Organ Chem Costin D Nenitzescu, Spl Independentei 202B, Bucharest 060023, Romania

[3] Maastricht Univ, Dept Data Sci & Knowledge Engn, Bouillonstr 8-10, NL-6211 LH Maastricht, Netherlands

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2018年 / 57卷 / 47期

关键词：

cationic polymerisation; polymers; ring-opening polymerisation; tautomerisation; CYCLIC IMINO ETHERS; POLY(2-ETHYL-2-OXAZOLINE) NANODOTS; SOLAR-CELLS; POLYMERIZATION; TEMPERATURE; 2-METHYL-2-OXAZOLINE; MACROMONOMERS; TELECHELICS;

D O I：

10.1002/anie.201807796

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Poly(2-alkyl-2-oxazoline)s (PAOx) are regaining interest for biomedical applications. However, their full potential is hampered by the inability to synthesise uniform high-molar mass PAOx. In this work, we proposed alternative intrinsic chain transfer mechanisms based on 2-oxazoline and oxazolinium chain-end tautomerisation and derived improved polymerization conditions to suppress chain transfer, allowing the synthesis of highly defined poly(2-ethyl-2-oxazoline) s up to ca. 50 kDa (dispersity (D) < 1.05) and defined polymers up to at least 300 kDa (D < 1.2). The determination of the chain transfer constants for the polymerisations hinted towards the tautomerisation of the oxazolinium chain end as most plausible cause for chain transfer. Finally, the method was applied for the preparation of up to 60 kDa molar mass copolymers of 2-ethyl2- oxazoline and 2-methoxycarbonylethyl-2-oxazoline.

引用

页码：15400 / 15404

页数：5

共 30 条

[1] POLYMERIZATION OF CYCLIC IMINO ETHERS .I. OXAZOLINES [J].