Heterogeneity Between Genetic Variants as a Proxy for Pleiotropy in Mendelian Randomization Reply

被引：2
|
作者：
Nazarzadeh, Milad [1 ,2 ,3 ]
Rahimi, Kazem [1 ,2 ,4 ]
机构：
[1] Univ Oxford, George Inst Global Hlth, 75 George St,Hayes House,1st Floor, Oxford OX1 2BQ, England
[2] Univ Oxford, Oxford Martin Sch, Deep Med, Oxford, England
[3] Torbat Heydariyeh Univ Med Sci, Collaborat Ctr Meta Anal Res, Torbat Heydariyeh, Iran
[4] Oxford Univ Hosp NHS Fdn Trust, NIHR Oxford Biomed Res Ctr, Oxford, England
来源：
JAMA CARDIOLOGY | 2020年 / 5卷 / 01期
关键词：
D O I：
10.1001/jamacardio.2019.4284
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：108 / 108
页数：1
相关论文
共 50 条
  • [1] Heterogeneity Between Genetic Variants as a Proxy for Pleiotropy in Mendelian Randomization
    Gill, Dipender
    JAMA CARDIOLOGY, 2020, 5 (01) : 107 - 108
  • [2] Mendelian randomization and pleiotropy analysis
    Xiaofeng Zhu
    Quantitative Biology, 2021, 9 (02) : 122 - 132
  • [3] Mendelian randomization and pleiotropy analysis
    Zhu, Xiaofeng
    QUANTITATIVE BIOLOGY, 2021, 9 (02) : 122 - 132
  • [4] A Novel Method for Mendelian Randomization Analyses With Pleiotropy and Linkage Disequilibrium in Genetic Variants From Individual Data
    Wang, Yuquan
    Li, Tingting
    Fu, Liwan
    Yang, Siqian
    Hu, Yue-Qing
    FRONTIERS IN GENETICS, 2021, 12
  • [5] Pleiotropy-robust Mendelian randomization
    van Kippersluis, Hans
    Rietveld, Cornelius A.
    INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2018, 47 (04) : 1279 - 1288
  • [6] Mendelian randomization and genetic pleiotropy analysis for the connection between inflammatory bowel disease and Alzheimer's disease
    Wu, Yuxuan
    Yan, Yu
    Qi, Jike
    Liu, Yuxin
    Wang, Ting
    Chen, Hao
    Guan, Xinying
    Zheng, Chu
    Zeng, Ping
    PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2025, 136
  • [7] Pleiotropy robust methods for multivariable Mendelian randomization
    Grant, Andrew J.
    Burgess, Stephen
    STATISTICS IN MEDICINE, 2021, 40 (26) : 5813 - 5830
  • [8] Mendelian randomization incorporating uncertainty about pleiotropy
    Thompson, John R.
    Minelli, Cosetta
    Bowden, Jack
    Del Greco, Fabiola M.
    Gill, Dipender
    Jones, Elinor M.
    Shapland, Chin Yang
    Sheehan, Nuala A.
    STATISTICS IN MEDICINE, 2017, 36 (29) : 4627 - 4645
  • [9] Constrained instruments and their application to Mendelian randomization with pleiotropy
    Jiang, Lai
    Oualkacha, Karim
    Didelez, Vanessa
    Ciampi, Antonio
    Rosa-Neto, Pedro
    Benedet, Andrea L.
    Mathotaarachchi, Sulantha
    Richards, John Brent
    Greenwood, Celia M. T.
    GENETIC EPIDEMIOLOGY, 2019, 43 (04) : 373 - 401
  • [10] Factorial Mendelian randomization: using genetic variants to assess interactions
    Rees, Jessica M. B.
    Foley, Christopher N.
    Burgess, Stephen
    INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2020, 49 (04) : 1147 - 1158
12345