Can the ischemia-reperfusion syndrome in transplanted kidneys procured from non-heart-beating donors be influenced by adding selenium into the reperfusion solution?: An experimental study

被引：6
作者：
Treska, V
Kuntscher, V
Molácek, J
Kobr, J
Racek, J
Trefil, L
机构：
[1] Univ Hosp Plzen, Dept Surg, Childrens Clin, Plzen 30460, Czech Republic
[2] Univ Hosp Plzen, Inst Clin Biochem & Lab Diagnost, Plzen 30460, Czech Republic
来源：
TRANSPLANTATION PROCEEDINGS | 2003年 / 35卷 / 04期
关键词：
D O I：
10.1016/S0041-1345(03)00466-4
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The ischemic-reperfusion syndrome significantly influences the function of a kidney transplanted from a non-heart-beating donor (NHBD). The animal model of a NHBD was used to monitor the influence of exogenous addition of selenium into the reperfusion solution (HTK, Custodiol) with respect to the formation of free oxygen radicals at 0 to 120 minutes after the NHBD transplantation. This maneuvers produced a statistically significant decrease in malondialdehyde concentration, an indicator of free oxygen radicals in the venous blood of the transplanted kidney. The augmentation of the antioxidative capacity of the preservation solution might be a possible route to improve the function of kidneys transplanted from NHBDs.
引用
收藏
页码：1584 / 1586
页数：3
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