Obstructive sleep apnea treatment outcomes pilot study

被引:55
作者
Piccirillo, JF
Gates, GA
White, DL
Schectman, KB
机构
[1] Washington Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Clin Outcomes Res Off, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Dept Otolaryngol, St Louis, MO 63110 USA
[3] Washington Univ, Sch Med, Div Biostat, St Louis, MO 63110 USA
关键词
D O I
10.1016/S0194-5998(98)70277-3
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Approximately 40 million Americans have chronic sleep disorders, the most serious of which is obstructive sleep apnea, The goals of this research were to serve as a demonstration project for a multicenter treatment outcomes research project for patients with obstructive sleep apnea, A clinical-severity staging system was created to control for important differences in the severity of sleep apnea among the enrolled patients. A disease-specific quality-of-life measure was used in this project to measure, from the patient's perspective, important pretreatment and posttreatment physical, functional, and emotional aspects of obstructive sleep apnea, Adults with apnea indexes greater than 5 who had not previously undergone uvulopalatoplasty were eligible. In total 142 patients were enrolled from eight otolaryngology practices, The mean age was 48 years, 112 were men, and 114 were white, The mean pretreatment apnea index was 40.0, and the mean respiratory distress index was 60.5. Seventy-one patients received continuous positive airway pressure, and 48 patients received surgery, Outcomes were assessed from scores on patient-based general and disease-specific health status measures 4 months after enrollment. The short duration of follow-up and limited number of patients undergoing posttreatment polysomnograms prohibit any analysis of treatment effectiveness. Nevertheless, this research represents a step forward for the support of future outcomes research projects by organized otolaryngology.
引用
收藏
页码:833 / 844
页数:12
相关论文
共 57 条
  • [11] DETECTING ALCOHOLISM - THE CAGE QUESTIONNAIRE
    EWING, JA
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1984, 252 (14): : 1905 - 1907
  • [12] FEINSTEIN AR, 1990, MEDICINE, V69, P1
  • [13] Fleiss J. L, 1981, STAT METHODS RATES P, P212
  • [14] UNDIAGNOSED SLEEP-APNEA IN PATIENTS WITH ESSENTIAL-HYPERTENSION
    FLETCHER, EC
    DEBEHNKE, RD
    LOVOI, MS
    GORIN, AB
    [J]. ANNALS OF INTERNAL MEDICINE, 1985, 103 (02) : 190 - 195
  • [15] SURGICAL-CORRECTION OF ANATOMIC ABNORMALITIES IN OBSTRUCTIVE SLEEP-APNEA SYNDROME - UVULOPALATOPHARYNGOPLASTY
    FUJITA, S
    CONWAY, W
    ZORICK, F
    ROTH, T
    [J]. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1981, 89 (06) : 923 - 934
  • [16] GEORGE CF, 1987, LANCET, V2, P227
  • [17] Hays R D, 1993, Health Econ, V2, P217, DOI 10.1002/hec.4730020305
  • [18] MORTALITY AND APNEA INDEX IN OBSTRUCTIVE SLEEP-APNEA - EXPERIENCE IN 385 MALE-PATIENTS
    HE, J
    KRYGER, MH
    ZORICK, FJ
    CONWAY, W
    ROTH, T
    [J]. CHEST, 1988, 94 (01) : 9 - 14
  • [19] DAYTIME SLEEPINESS, SNORING, AND OBSTRUCTIVE SLEEP-APNEA - THE EPWORTH SLEEPINESS SCALE
    JOHNS, MW
    [J]. CHEST, 1993, 103 (01) : 30 - 36
  • [20] KALES A, 1984, LANCET, V2, P1005