Infrared Irradiation-Assisted Solvent-Free Pd-Catalyzed (Hetero)aryl-aryl Coupling via C-H Bond Activation

被引：15

作者：

Albano, Gianluigi ^{[1
]}

Decandia, Gianfranco ^{[1
,2
]}

Capozzi, Maria Annunziata M. ^{[1
]}

Zappimbulso, Nicola ^{[1
]}

Punzi, Angela ^{[1
]}

Farinola, Gianluca M. ^{[1
]}

机构：

[1] Univ Bari Aldo Moro, Dipartimento Chim, Via Orabona 4, I-70125 Bari, Italy

[2] Ist Proc Chimico Fis CNR IPCF, Dipartimento Chim, Via Orabona 4, I-70125 Bari, Italy

来源：

CHEMSUSCHEM | 2021年 / 14卷 / 16期

关键词：

C-H activation; C-C coupling; infrared irradiation; solvent-free; synthetic methods; DIRECT ARYLATION; MICROWAVE; ARYL; HETEROARENES; DERIVATIVES; EFFICIENT; ARENES; LIGAND; WATER; MILD;

D O I：

10.1002/cssc.202101070

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The increasing attention towards environmentally friendly synthetic protocols has boosted studies directed to the development of green and sustainable methods for direct C-H bond arylation of (hetero)arenes. In this context, here the infrared (IR) irradiation-assisted solvent-free Pd-catalyzed direct C-H bond arylation of (hetero)arenes was achieved. Several heteroaryl-aryl coupling reactions were described, also involving heterocycles commonly used as building blocks for the synthesis of organic semiconductors. The reaction tolerated many functional groups on the aromatic nuclei. The IR-irradiation as the energy source compared favorably with thermal heating and, in combination with solvent-free conditions, provided an important contribution to the development of protocols fitting with the principles of green chemistry.

引用

页码：3391 / 3401

页数：11

共 59 条

[1] Catalytic Direct Arylations in Polyethylene Glycol (PEG): Recyclable Palladium(0) Catalyst for C-H Bond Cleavages in the Presence of Air [J].