Complex liver cysts in Autosomal Dominant Polycystic Kidney Disease

被引:7
作者
Farooq, Zerwa [1 ,2 ]
Behzadi, Ashkan Heshmatzadeh [1 ,2 ]
Blumenfeld, Jon D. [3 ,4 ]
Zhao, Yize [5 ]
Prince, Martin R. [1 ,2 ]
机构
[1] Weill Cornell Med Ctr, Dept Radiol, New York, NY USA
[2] Columbia Coll Phys & Surg, Dept Radiol, New York, NY USA
[3] Rogosin Inst, New York, NY USA
[4] Weill Cornell Med Ctr, Div Nephrol Hypertens & Transplant Med, Dept Med, New York, NY USA
[5] Weill Cornell Med Coll, Dept Healthcare Policy & Res, New York, NY 10021 USA
基金
美国国家卫生研究院;
关键词
ADPKD; Liver; Complex cysts; Hemorrhage; Infection; OBSTRUCTIVE-JAUNDICE; HEMORRHAGE;
D O I
10.1016/j.clinimag.2017.07.014
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose: To determine prevalence of complex liver cysts in Autosomal Dominant Polycystic Kidney Disease (ADPKD). Methods: Abdominal MRI in 186 ADPKD subjects were evaluated by two independent observers to determine prevalence of complex liver cysts. Results: 23 (12%) of subjects, had at least 1 complex cyst. Only 8 (4%) were reported to have a complex cyst prospectively, representing an under-reporting rate of 65%. Median total cyst volume was 66-times greater for subjects with complex cysts compared to subjects without (p < 0.0001). Conclusion: Complex hepatic cysts were observed in 12% of ADPKD cases, occurring more frequently in livers with extensive cystic involvement. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码:98 / 101
页数:4
相关论文
共 10 条
[1]   Magnetic resonance imaging evaluation of hepatic cysts in early autosomal-dominant polycystic kidney disease: The consortium for radiologic imaging studies of polycystic kidney disease cohort [J].
Bae, Kyongtae T. ;
Zhu, Fang ;
Chapman, Arlene B. ;
Torres, Vicente E. ;
Grantham, Jared J. ;
Guay-Woodford, Lisa M. ;
Baumgarten, Deborah A. ;
King, Bernard F., Jr. ;
Wetzel, Louis H. ;
Kenney, Philip J. ;
Brummer, Marijn E. ;
Bennett, William M. ;
Klahr, Saulo ;
Meyers, Catherine M. ;
Zhang, Xiaoling ;
Thompson, Paul A. ;
Miller, J. Philip .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2006, 1 (01) :64-69
[2]   Polycystic liver disease: an overview of pathogenesis, clinical manifestations and management [J].
Cnossen, Wybrich R. ;
Drenth, Joost P. H. .
ORPHANET JOURNAL OF RARE DISEASES, 2014, 9
[3]   Haemorrhagic hepatic cyst: a differential diagnosis of cystic tumour [J].
Hagiwara, A ;
Inoue, Y ;
Shutoh, T ;
Kinoshita, H ;
Wakasa, K .
BRITISH JOURNAL OF RADIOLOGY, 2001, 74 (879) :270-272
[4]   Liver Involvement in Early Autosomal-Dominant Polycystic Kidney Disease [J].
Hogan, Marie C. ;
Abebe, Kaleab ;
Torres, Vicente E. ;
Chapman, Arlene B. ;
Bae, Kyongtae T. ;
Tao, Cheng ;
Sun, Hongliang ;
Perrone, Ronald D. ;
Steinman, Theodore I. ;
Braun, William ;
Winklhofer, Franz T. ;
Miskulin, Dana C. ;
Rahbari-Oskoui, Frederic ;
Brosnahan, Godela ;
Masoumi, Amirali ;
Karpov, Irina O. ;
Spillane, Susan ;
Flessner, Michael ;
Moore, Charity G. ;
Schrier, Robert W. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2015, 13 (01) :155-+
[5]  
Hogan Marie C, 2010, Adv Chronic Kidney Dis, V17, pe1, DOI 10.1053/j.ackd.2010.01.005
[6]   Pancreatic Cysts in Autosomal Dominant Polycystic Kidney Disease: Prevalence and Association with PKD2 Gene Mutations [J].
Kim, Jin Ah ;
Blumenfeld, Jon D. ;
Chhabra, Shalini ;
Dutruel, Silvina P. ;
Thimmappa, Nanda Deepa ;
Bobb, Warren O. ;
Donahue, Stephanie ;
Rennert, Hanna E. ;
Tan, Adrian Y. ;
Giambrone, Ashley E. ;
Prince, Martin R. .
RADIOLOGY, 2016, 280 (03) :762-770
[7]   POLYCYSTIC LIVER-DISEASE WITH OBSTRUCTIVE-JAUNDICE - TREATMENT WITH ULTRASOUND-GUIDED CYST ASPIRATION [J].
LERNER, ME ;
ROSHKOW, JE ;
SMITHLINE, A ;
NG, C .
GASTROINTESTINAL RADIOLOGY, 1992, 17 (01) :46-48
[8]  
Rosenfeld L, 2001, GASTROEN CLIN BIOL, V25, P818
[9]   Clinical features of cyst infection and hemorrhage in ADPKD: new diagnostic criteria [J].
Suwabe, Tatsuya ;
Ubara, Yoshifumi ;
Sumida, Keiichi ;
Hayami, Noriko ;
Hiramatsu, Rikako ;
Yamanouchi, Masayuki ;
Hasegawa, Eiko ;
Hoshino, Junichi ;
Sawa, Naoki ;
Saitoh, Satoshi ;
Okuda, Itsuko ;
Takaichi, Kenmei .
CLINICAL AND EXPERIMENTAL NEPHROLOGY, 2012, 16 (06) :892-902
[10]   Fatal liver cyst rupture in polycystic liver disease complicated with autosomal dominant polycystic kidney disease: A case report [J].
Tong, Fang ;
Liang, Yue ;
Zhang, Lin ;
Li, Wenhe ;
Chen, Peng ;
Duan, Yijie ;
Zhou, Yiwu .
FORENSIC SCIENCE INTERNATIONAL, 2016, 262 :E5-E8