Green Synthesis of Pyrido[2,1-a]isoquinolines and Pyrido[1,2-a]quinolines by Using ZnO Nanoparticles

被引：29

作者：

Ghazvini, Maryam ^{[1
]}

Sheikholeslami-Farahani, Fatemeh ^{[2
]}

Soleimani-Amiri, Somayeh ^{[3
]}

Salimifard, Masoomeh ^{[4
]}

Rostamian, Rezvaneh ^{[4
]}

机构：

[1] Payame Noor Univ, Dept Chem, POB 3971189451, Tehran, Iran

[2] Islamic Azad Univ, Firoozkooh Branch, Dept Chem, Firoozkooh, Iran

[3] Islamic Azad Univ, Karaj Branch, Dept Chem, Karaj, Iran

[4] Islamic Azad Univ, Qaemshahr Branch, Dept Chem, Qaemshahr, Iran

来源：

SYNLETT | 2018年 / 29卷 / 04期

关键词：

pyridoisoquinolines; pyridoquinolines; solvent-free synthesis; dialkyl acetylenedicarboxylates; nanoparticles; zinc oxide; MULTICOMPONENT SYNTHESIS; 4-COMPONENT SYNTHESIS; SOLVENT-FREE; INHIBITORS; POLYMERIZATION; HETEROCYCLES; QUINOLINES; TEMPLATE; ALCOHOL; AMINES;

D O I：

10.1055/s-0036-1591509

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrido[2,1-a]isoquinoline and pyrido[1,2-a]quinoline derivatives have been produced in good yields by the reaction of isoquinoline or quinoline, activated acetylenic compounds, alpha-halo ketones, and triphenylphosphine in the presence of ZnO nanoparticles (NPs) as an efficient catalyst under solvent-free conditions at room temperature. The reaction workup is easy, and the products can be readily separated from the reaction mixture. ZnO NPs markedly improved the yield of the product. The catalyst showed significant reusable activity.

引用

页码：493 / 496

页数：4

共 48 条

[1] Silica supported tungstic acid (STA): an efficient catalyst for the synthesis of bis-spiro piperidine derivatives under milder condition [J].