Prescription Drugs Used in Insomnia

被引：15

作者：

Dujardin, Sylvie ^{[1
]}

Pijpers, Angelique ^{[1
]}

Pevernagie, Dirk ^{[1
,2
]}

机构：

[1] Sleep Med Ctr Kempenhaeghe, POB 61, Heeze 5590 AB, Netherlands

[2] Univ Ghent, Fac Med & Hlth Sci, Dept Internal Med & Paediat, Corneel Heymanslaan 10, Ghent 9000, Belgium

来源：

SLEEP MEDICINE CLINICS | 2020年 / 15卷 / 02期

关键词：

Chronic insomnia; Prescription drugs; Pharmacotherapy; Sleep-effect; OREXIN RECEPTOR ANTAGONIST; RANDOMIZED CLINICAL-TRIAL; DOXEPIN; MG; DOUBLE-BLIND; MELATONIN RECEPTORS; SLEEP EEG; PHARMACOLOGICAL-TREATMENT; BENZODIAZEPINE HYPNOTICS; THERAPEUTIC-EFFICACY; OUTPATIENT TRIAL;

D O I：

10.1016/j.jsmc.2020.02.002

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This article reviews the effects on sleep of prescription drugs that are commonly prescribed for chronic insomnia in adults. The following groups are discussed: benzodiazepines and their receptor agonists, the dual orexin receptor antagonist suvorexant, melatonin and its receptor agonists, sedating antidepressants, and antipsychotics. Together with the neurobiologic and pharmacologic properties of these drugs, clinical effects are described, including subjective and objective effects on sleep duration, continuity, and architecture. Medical prescription information is given when available. Recently published American and European guidelines for the treatment of insomnia serve as reference frame.

引用

页码：133 / +

页数：14

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