Regio- and stereoselective homocoupling of γ-arylated tert-propargyl alcohols with liberation of a ketone molecule and successive cyclization to produce fluorescent dihydrofuran derivatives

被引：93

作者：

Funayama, A ^{[1
]}

Satoh, T ^{[1
]}

Miura, M ^{[1
]}

机构：

[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 44期

关键词：

D O I：

10.1021/ja055452w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1,1-Disubstituted 3-aryl-2-propyn-1-ols undergo unprecedented regio- and stereoselective homocoupling with liberation of a ketone molecule in the presence of a rhodium catalyst to give the corresponding 2-hydroxymethyl-(E)-enynes. The subsequent cyclization of the enynes in the presence of a base affords fluorescent 2,3-dihydrofuran derivatives. Copyright © 2005 American Chemical Society.

引用

页码：15354 / 15355

页数：2

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