Effects of butyltin compounds on phagocytic activity of hemocytes from three marine bivalves

被引:42
作者
Bouchard, N
Pelletier, É
Fournier, M
机构
[1] Inst Natl Rech Sci Oceanol, Rimouski, PQ G5L 3A1, Canada
[2] Univ Quebec, Dept Oceanog, Rimouski, PQ G5L 3A1, Canada
[3] Univ Quebec, TOXEN, Montreal, PQ H3C 3P8, Canada
[4] Fisheries & Oceans Canada, Maurice Lamontagne Inst, Mont Joli, PQ G5H 3Z4, Canada
关键词
butyltins; immunotoxicity; marine bivalves; phagocytosis;
D O I
10.1002/etc.5620180321
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Effects of tributyltin (TBT), dibutyltin (DBT), and monobutyltin (MBT) on the in vitro phagocytic activity of hemocytes from three marine bivalve species, Mytilus edulis, Mya arenaria, and Mactromeris polynyma, were determined using flow cytometry. Phagocytosis was reduced with increasing doses of TBT and DBT The toxicity of butyltins on hemocytes decreased in the order DBT > TBT > MET, and comparison of the relative sensitivity of the three species showed that blue mussels (M. edulis) were more tolerant of butyltin compounds than both clam species. Toxicity mechanisms of butyltins are discussed and compared to those of other metals.
引用
收藏
页码:519 / 522
页数:4
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