In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography

被引:425
作者
Nassif, N
Cense, B
Park, BH
Yun, SH
Chen, TC
Bouma, BE
Tearney, GJ
de Boer, JF
机构
[1] Harvard Univ, Sch Med, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
[3] Massachusetts Eye & Ear Infirm, Boston, MA 02114 USA
关键词
D O I
10.1364/OL.29.000480
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
An ultrahigh-speed spectral domain optical coherence tomography (SD-OCT) system is presented that achieves acquisition rates of 29,300 depth profiles/s. The sensitivity of SD-OCT and time domain OCT (TD-OCT) are experimentally compared, demonstrating a 21.7-dB improvement of SD-OCT over TD-OCT. In. vivo images of the human retina are presented, demonstrating the ability to acquire high-quality structural images with an axial resolution of 6 mum at ultrahigh speed and with an ocular exposure level of less than 600 muW. (C) 2004 Optical Society of America.
引用
收藏
页码:480 / 482
页数:3
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