Cardiac magnetic resonance findings predict increased resource utilization in elective coronary artery bypass grafting

被引:3
作者
Berry, Colin [1 ,2 ]
Zimmerli, Lukas U. [1 ,2 ]
Steedman, Tracey [1 ,2 ]
Foster, John E. [2 ]
Dargie, Henry J. [2 ,3 ]
Berg, Geoffrey A. [3 ]
Dominiczak, Anna F. [1 ,2 ]
Delles, Christian [1 ,2 ]
机构
[1] Univ Glasgow, British Heart Fdn Glasgow Cardiovasc Res Ctr, Glasgow, Lanark, Scotland
[2] Western Infirm & Associated Hosp, Glasgow Cardiac Magnet Resonance Unit, Glasgow, Lanark, Scotland
[3] Western Infirm & Associated Hosp, Dept Cardiac Surg, Glasgow, Lanark, Scotland
基金
英国惠康基金;
关键词
coronary artery bypass surgery (CABG); coronary artery disease; cardiac magnetic resonance (CMR); echocardiography; left ventricular function; resource utilization;
D O I
10.1042/CS20070337
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Morbidity following CABG (coronary artery bypass grafting) is difficult to predict and leads to increased healthcare costs. We hypothesized that pre-operative CMR (cardiac magnetic resonance) findings would predict resource utilization in elective CABG. Over a 12-month period, patients requiring elective CABG were invited to undergo CMR I day prior to CABG. Gadolinium-enhanced CMR was performed using a trueFISP inversion recovery sequence on a 1.5 tesla, scanner (Sonata; Siemens). Clinical data were collected prospectively. Admission costs were quantified based on standardized actual cost/day. Admission cost greater than the median was defined as 'increased'. Of 458 elective CABG cases, 45 (10 %) underwent pre-operative CMR. Pre-operative characteristics [mean (S.D.) age, 64 (9) years, mortality (I %) and median (interquartile range) admission duration, 7 (6-8) days] were similar in patients who did or did not undergo CMR. In the patients undergoing CMR, eight (18 %) and 11 (24 %) patients had reduced LV (left ventricular) systolic function by CMR [LVEF (LV ejection fraction) < 55 %] and echocardiography respectively. LE (late enhancement) with gadolinium was detected in 17 (38 %) patients. The average cost/day was $2723. The median (interquartile range) admission cost was $19059 ($10891-157917). CMR LVEF {OR (odds ratio), 0.93 [95 % CI (confidence interval), 0.87-0.99]; P = 0.03} and SV (stroke volume) index [OR 1.07 (95 % CI, 1.00- 1.14); P = 0.02] predicted increased admission cost. CMR LVEF (P = 0.08) and EuroScore tended to predict actual admission cost (P = 0.09), but SV by CMR (P = 0.16) and LV function by echocardiography (P = 0.95) did not. In conclusion, in this exploratory investigation, pre-operative CMR findings predicted admission duration and increased admission cost in elective CABG surgery. The cost-effectiveness of CMR in risk stratification in elective CABG surgery merits prospective assessment.
引用
收藏
页码:423 / 430
页数:8
相关论文
共 35 条
[1]   Comparison of right ventricular volume measurements between axial and short axis orientation using steady-state free precession magnetic resonance imaging [J].
Alfakih, K ;
Plein, S ;
Bloomer, T ;
Jones, T ;
Ridgway, J ;
Sivananthan, M .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 2003, 18 (01) :25-32
[2]  
*AM HEART ASS, 2002, HEART DIS STROK STAT
[3]   Recovery of left ventricular function after primary angioplasty for acute myocardial infarction [J].
Baks, T ;
van Geuns, RJ ;
Biagini, E ;
Wielopolski, P ;
Mollet, NR ;
Cademartiri, F ;
Boersma, E ;
van der Giessen, WJ ;
Krestin, GP ;
Duncker, DJ ;
Serruys, PW ;
de Feyter, PJ .
EUROPEAN HEART JOURNAL, 2005, 26 (11) :1070-1077
[4]   Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance - Are they interchangeable? [J].
Bellenger, NG ;
Burgess, MI ;
Ray, SG ;
Lahiri, A ;
Coats, AJS ;
Cleland, JGF ;
Pennell, DJ .
EUROPEAN HEART JOURNAL, 2000, 21 (16) :1387-1396
[5]   Economics of chronic heart failure [J].
Berry, C ;
Murdoch, DR ;
McMurray, JJV .
EUROPEAN JOURNAL OF HEART FAILURE, 2001, 3 (03) :283-291
[6]   The prevalence, nature, and importance of hematologic abnormalities in heart failure [J].
Berry, Colin ;
Norrie, John ;
Hogg, Karen ;
Brett, Michael ;
Stevenson, Karen ;
McMurray, John J. V. .
AMERICAN HEART JOURNAL, 2006, 151 (06) :1313-1321
[7]  
*BRIT HEART FDN, 2006, BRIT HEART FDN HEART, P61
[8]   Outcomes and cost of coronary artery bypass graft surgery-in the United States and Canada [J].
Eisenberg, MJ ;
Filion, KB ;
Azoulay, A ;
Brox, AC ;
Haider, S ;
Pilote, L .
ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (13) :1506-1513
[9]   A decade of change - Risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990-1999: A report from the STS National Database Committee and the Duke Clinical Research Institute [J].
Ferguson, TB ;
Hammill, BG ;
Peterson, ED ;
DeLong, ER ;
Grover, FL .
ANNALS OF THORACIC SURGERY, 2002, 73 (02) :480-489
[10]   Contrast-enhanced magnetic resonance imaging of myocardium at risk - Distinction between reversible and irreversible injury throughout infarct healing [J].
Fieno, DS ;
Kim, RJ ;
Chen, EL ;
Lomasney, JW ;
Klocke, FJ ;
Judd, RM .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (06) :1985-1991