coronary artery bypass surgery (CABG);
coronary artery disease;
cardiac magnetic resonance (CMR);
echocardiography;
left ventricular function;
resource utilization;
D O I:
10.1042/CS20070337
中图分类号:
R-3 [医学研究方法];
R3 [基础医学];
学科分类号:
1001 ;
摘要:
Morbidity following CABG (coronary artery bypass grafting) is difficult to predict and leads to increased healthcare costs. We hypothesized that pre-operative CMR (cardiac magnetic resonance) findings would predict resource utilization in elective CABG. Over a 12-month period, patients requiring elective CABG were invited to undergo CMR I day prior to CABG. Gadolinium-enhanced CMR was performed using a trueFISP inversion recovery sequence on a 1.5 tesla, scanner (Sonata; Siemens). Clinical data were collected prospectively. Admission costs were quantified based on standardized actual cost/day. Admission cost greater than the median was defined as 'increased'. Of 458 elective CABG cases, 45 (10 %) underwent pre-operative CMR. Pre-operative characteristics [mean (S.D.) age, 64 (9) years, mortality (I %) and median (interquartile range) admission duration, 7 (6-8) days] were similar in patients who did or did not undergo CMR. In the patients undergoing CMR, eight (18 %) and 11 (24 %) patients had reduced LV (left ventricular) systolic function by CMR [LVEF (LV ejection fraction) < 55 %] and echocardiography respectively. LE (late enhancement) with gadolinium was detected in 17 (38 %) patients. The average cost/day was $2723. The median (interquartile range) admission cost was $19059 ($10891-157917). CMR LVEF {OR (odds ratio), 0.93 [95 % CI (confidence interval), 0.87-0.99]; P = 0.03} and SV (stroke volume) index [OR 1.07 (95 % CI, 1.00- 1.14); P = 0.02] predicted increased admission cost. CMR LVEF (P = 0.08) and EuroScore tended to predict actual admission cost (P = 0.09), but SV by CMR (P = 0.16) and LV function by echocardiography (P = 0.95) did not. In conclusion, in this exploratory investigation, pre-operative CMR findings predicted admission duration and increased admission cost in elective CABG surgery. The cost-effectiveness of CMR in risk stratification in elective CABG surgery merits prospective assessment.