A Direct Palladium-Catalyzed Route for the Synthesis of Benzo[a]carbazoles through Sequential C-C Bond Formation and C-H Bond Functionalization

被引：25
|
作者：
Kianmehr, Ebrahim [1 ]
Ghanbari, Mohammad [1 ]
机构：
[1] Univ Tehran, Coll Sci, Sch Chem, Tehran 1417614411, Iran
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 2012卷 / 02期
关键词：
Homogeneous catalysis; Palladium; C-C coupling; Heterocycles; Synthetic methods; POLYCYCLIC AROMATIC-HYDROCARBONS; BIOLOGICAL EVALUATION; EFFICIENT SYNTHESIS; ARYLATION; COMPLEXES; ANALOGS; DERIVATIVES; ANNULATION; MECHANISM; INDOLES;
D O I：
10.1002/ejoc.201101401
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A direct palladium-catalyzed route for the synthesis of novel benzo[a]carbazoles through sequential C-C bond formation and C-H bond functionalization by using readily available starting materials has been demonstrated. Prominent among the advantages of this new method are operational simplicity and good yields.
引用
收藏
页码：256 / 259
页数：4
相关论文
共 50 条
  • [1] A Direct Palladium-Catalyzed Route to Selectively Substituted Carbazoles through Sequential C-C and C-N Bond Formation: Synthesis of Carbazomycin A
    Della Ca, Nicola
    Sassi, Giovanni
    Catellani, Marta
    ADVANCED SYNTHESIS & CATALYSIS, 2008, 350 (14-15) : 2179 - 2182
  • [2] Palladium-catalyzed method for the synthesis of carbazoles via tandem C-H functionalization and C-N bond formation
    Tsang, W. C. Peter
    Munday, Rachel H.
    Brasche, Gordon
    Zheng, Nan
    Buchwald, Stephen L.
    JOURNAL OF ORGANIC CHEMISTRY, 2008, 73 (19): : 7603 - 7610
  • [3] Palladium-Catalyzed intramolecular C-H Activation/C-C Bond Formation: A Straightforward Synthesis of Phenanthridines
    Peng, Jinsong
    Chen, Tonghui
    Chen, Chunxia
    Li, Bin
    JOURNAL OF ORGANIC CHEMISTRY, 2011, 76 (22): : 9507 - 9513
  • [4] Palladium-catalyzed C-N bond formation via direct C-H bond functionalization. Recent developments in heterocyclic synthesis
    Beccalli, Egle M.
    Broggini, Gianluigi
    Fasana, Andrea
    Rigamonti, Micol
    JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2011, 696 (01) : 277 - 295
  • [5] Combined C-H functionalization/C-N bond formation route to carbazoles
    Tsang, WCP
    Zheng, N
    Buchwald, SL
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (42) : 14560 - 14561
  • [6] Palladium-catalyzed C-H bond functionalization of amine derivatives
    Nadres, Enrico T.
    Daugulis, Olafs
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [7] Palladium-Catalyzed C-H Bond Functionalization with Arylsulfonyl Chlorides
    Zhao, Xiaodan
    Dimitrijevic, Elena
    Dong, Vy M.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (10) : 3466 - +
  • [8] Palladium-Catalyzed Allylic C-H Bond Functionalization of Olefins
    Liu, Guosheng
    Wu, Yichen
    C-H ACTIVATION, 2010, 292 : 195 - 209
  • [9] Palladium-catalyzed C-H bond functionalization of C6-arylpurines
    Guo, Hai-Ming
    Rao, Wei-Hao
    Niu, Hong-Ying
    Jiang, Li-Li
    Meng, Ge
    Jin, Jia-Jia
    Yang, Xi-Ning
    Qu, Gui-Rong
    CHEMICAL COMMUNICATIONS, 2011, 47 (19) : 5608 - 5610
  • [10] Intramolecular cycloisomerization of a propanes via NHC palladium-catalyzed cascade C-C bond cleavage/C-H activation/C-C bond formation
    Yang, Yewei
    Huang, Xian
    SYNLETT, 2008, (09) : 1366 - 1370
12345