Neonatal herpes simplex virus

被引：6

作者：

Berardi, Alberto ^{[1
]}

Lugli, Licia ^{[1
]}

Rossi, Cecilia ^{[1
]}

Maria, Chiara Laguardia ^{[1
]}

Guidotti, Isotta ^{[1
]}

Gallo, Claudio ^{[1
]}

Ferrari, Fabrizio ^{[1
]}

机构：

[1] Univ Policlin Modena, Azienda Osped, Neonatal Intens Care Unit, I-41124 Modena, Italy

来源：

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2011年 / 24卷

关键词：

Herpes simplex virus; newborn; infection; antiviral treatment; prevention; INFECTION; PREGNANCY; DIAGNOSIS; THERAPY;

D O I：

10.3109/14767058.2011.607560

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in utero, the transmission frequently occurs during delivery. The disease may be disseminated, localized to the central nervous system, or involving skin, eye and/or mouth. Mortality rates markedly decreased with high-dose antiviral treatment. Diagnosis of neonatal infection is based on viral isolation from ulcerated vesicles or by scarifying mucocutaneous lesions. Recently polymerase chain reaction plays a central role for both viral detection (skin, mucosal, cerebrospinal fluid samples) and response to therapy. Vertical transmission may be decreased by prophylactic antiviral treatment.

引用

页码：88 / 90

页数：3

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