Chromosome assignment of 115 expressed sequence tags (ESTs) from human skeletal muscle

被引：6
|
作者：
Muraro, T
Stephan, D
Tiso, N
Zimbello, R
Danieli, GA
Hoffman, EH
Valle, G
Lanfranchi, G
机构：
[1] UNIV PADUA,CRIBI BIOTECHNOL CTR,I-35121 PADUA,ITALY
[2] UNIV PITTSBURGH,SCH MED,DEPT MOL GENET & BIOCHEM,PITTSBURGH,PA 15261
[3] UNIV PADUA,DIPARTIMENTO BIOL,PADUA,ITALY
来源：
CYTOGENETICS AND CELL GENETICS | 1997年 / 76卷 / 3-4期
关键词：
D O I：
10.1159/000134533
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The chromosome assignment of 115 expressed sequence tags (ESTs) from human skeletal muscle, 101 of which identify unknown human genes, is reported. The ESTs were selected among over 4,000 obtained from systematic sequencing of a skeletal muscle cDNA library containing 3' portions of the mRNAs. Chromosome assignments were obtained by PCR amplification of two panels of human x rodent somatic cell hybrids. Analysis of these preliminary data suggests a nonrandom distribution of muscle ESTs in the human chromosome complement. The unexpected occurrence of multiple chromosome localizations for some ESTs is discussed.
引用
收藏
页码：144 / 152
页数：9
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