Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019

被引：17
作者：
Li, Lin [1 ]
Zhou, Qi [2 ]
Xu, Jiancheng [1 ]
机构：
[1] First Hosp Jilin Univ, Dept Lab Med, Changchun 130021, Peoples R China
[2] First Hosp Jilin Univ, Dept Pediat, Changchun 130021, Peoples R China
来源：
BIOMED RESEARCH INTERNATIONAL | 2020年 / 2020卷
关键词：
ANGIOTENSIN-CONVERTING ENZYME-2; ACUTE RESPIRATORY SYNDROME; CLINICAL CHARACTERISTICS; SARS; OUTBREAK; WUHAN; INFLAMMATION; EXPRESSION; PNEUMONIA; COVID-19;
D O I：
10.1155/2020/7413673
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Some patients with coronavirus disease 2019 (COVID-19) show abnormal changes in laboratory myocardial injury markers, suggesting that patients with myocardial injury have a higher mortality rate than those without myocardial injury. This article reviews the possible mechanism of myocardial injury in patients with COVID-19. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the patients with COVID-19 in aspects of direct infection of myocardial injury, specific binding to functional receptors on cardiomyocytes, and immune-mediated myocardial injury. During hospitalization, the monitoring of laboratory myocardial injury markers in patients of COVID-19 should be strengthened.
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页数：7
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