Changes of Laboratory Cardiac Markers and Mechanisms of Cardiac Injury in Coronavirus Disease 2019

被引：17
作者：
Li, Lin [1 ]
Zhou, Qi [2 ]
Xu, Jiancheng [1 ]
机构：
[1] First Hosp Jilin Univ, Dept Lab Med, Changchun 130021, Peoples R China
[2] First Hosp Jilin Univ, Dept Pediat, Changchun 130021, Peoples R China
来源：
BIOMED RESEARCH INTERNATIONAL | 2020年 / 2020卷
关键词：
ANGIOTENSIN-CONVERTING ENZYME-2; ACUTE RESPIRATORY SYNDROME; CLINICAL CHARACTERISTICS; SARS; OUTBREAK; WUHAN; INFLAMMATION; EXPRESSION; PNEUMONIA; COVID-19;
D O I：
10.1155/2020/7413673
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Some patients with coronavirus disease 2019 (COVID-19) show abnormal changes in laboratory myocardial injury markers, suggesting that patients with myocardial injury have a higher mortality rate than those without myocardial injury. This article reviews the possible mechanism of myocardial injury in patients with COVID-19. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the patients with COVID-19 in aspects of direct infection of myocardial injury, specific binding to functional receptors on cardiomyocytes, and immune-mediated myocardial injury. During hospitalization, the monitoring of laboratory myocardial injury markers in patients of COVID-19 should be strengthened.
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页数：7
相关论文
共 58 条
[1]  
Ai J, 2020, CROSS SECTIONAL STUD, DOI [10.1101/2020.02.19.20025023, DOI 10.1101/2020.02.19.20025023]
[2]   SARS-CoV-2 inflames the heart. The importance of awareness of myocardial injury in COVID-19 patients [J].
Ammirati, Enrico ;
Wang, Dao Wen .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2020, 311 :122-123
[3]  
Caramelo F., 2020, MEDRXIV, DOI [10.1101/2020.02.24.20027268, DOI 10.1101/2020.02.24.20027268]
[4]   Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records [J].
Chen, Huijun ;
Guo, Juanjuan ;
Wang, Chen ;
Luo, Fan ;
Yu, Xuechen ;
Zhang, Wei ;
Li, Jiafu ;
Zhao, Dongchi ;
Xu, Dan ;
Gong, Qing ;
Liao, Jing ;
Yang, Huixia ;
Hou, Wei ;
Zhang, Yuanzhen .
LANCET, 2020, 395 (10226) :809-815
[5]  
Chen J, 2020, RETROSPECTIVE ANAL C, DOI [10.1101/2020.03.09.20033068., 10.1101/2020.03.09.20033068]
[6]  
Chen L, 2020, Zhonghua Jie He He Hu Xi Za Zhi, V43, pE005, DOI 10.3760/cma.j.issn.1001-0939.2020.0005
[7]   Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study [J].
Chen, Nanshan ;
Zhou, Min ;
Dong, Xuan ;
Qu, Jieming ;
Gong, Fengyun ;
Han, Yang ;
Qiu, Yang ;
Wang, Jingli ;
Liu, Ying ;
Wei, Yuan ;
Xia, Jia'an ;
Yu, Ting ;
Zhang, Xinxin ;
Zhang, Li .
LANCET, 2020, 395 (10223) :507-513
[8]   Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR (Publication with Expression of Concern) [J].
Corman, Victor M. ;
Landt, Olfert ;
Kaiser, Marco ;
Molenkamp, Richard ;
Meijer, Adam ;
Chu, Daniel K. W. ;
Bleicker, Tobias ;
Bruenink, Sebastian ;
Schneider, Julia ;
Schmidt, Marie Luisa ;
Mulders, Daphne G. J. C. ;
Haagmans, Bart L. ;
van der Veer, Bas ;
van den Brink, Sharon ;
Wijsman, Lisa ;
Goderski, Gabriel ;
Romette, Jean-Louis ;
Ellis, Joanna ;
Zambon, Maria ;
Peiris, Malik ;
Goossens, Herman ;
Reusken, Chantal ;
Koopmans, Marion P. G. ;
Drosten, Christian .
EUROSURVEILLANCE, 2020, 25 (03) :23-30
[9]   Angiotensin-converting enzyme 2 is an essential regulator of heart function [J].
Crackower, MA ;
Sarao, R ;
Oudit, GY ;
Yagil, C ;
Kozieradzki, I ;
Scanga, SE ;
Oliveira-dos-Santos, AJ ;
da Costa, J ;
Zhang, LY ;
Pei, Y ;
Scholey, J ;
Ferrario, CM ;
Manoukian, AS ;
Chappell, MC ;
Backx, PH ;
Yagil, Y ;
Penninger, JM .
NATURE, 2002, 417 (6891) :822-828
[10]   Suspected myocardial injury in patients with COVID-19: Evidence from front-line clinical observation in Wuhan, China [J].
Deng, Qing ;
Hu, Bo ;
Zhang, Yao ;
Wang, Hao ;
Zhou, Xiaoyang ;
Hu, Wei ;
Cheng, Yuting ;
Yan, Jie ;
Ping, Haiqin ;
Zhou, Qing .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2020, 311 :116-121
123456