Carbamazepine induced hyponatremia

被引：0

作者：

Inamura, T ^{[1
]}

Kuba, H ^{[1
]}

Morioka, T ^{[1
]}

Muratani, H ^{[1
]}

Muraishi, M ^{[1
]}

Hisada, K ^{[1
]}

Fukui, M ^{[1
]}

机构：

[1] Kyushu Univ, Fac Med, Neurol Inst, Dept Neurosurg,Higashi Ku, Fukuoka 8128582, Japan

来源：

NEUROLOGICAL SURGERY | 1999年 / 27卷 / 01期

关键词：

carbamazepine; hyponatremia; syndrome of inappropriate antidiuretic hormone (SIADH);

D O I：

暂无

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Carbamazepine (CBZ) is a drug which can induce the syndrome of inappropriate antidiuretic hormone (SIADH). Until 1980's, there were reports regarding CBZ-induced SIADH, but it is rarely reported these days. We here report two cases of CBZ-induced SIADH. Hyponatremia in these cases was rapidly improved by withdrawal of administration of CBZ. According to the previous :reports, the rate of hyponatremia in patients receiving CBZ is not small. It ranges from 4.8% to 31%. As CBZ is frequently used for patients with epilepsy and neuralgia, not only their blood CBZ concentration but also their serum Na level should be monitored.

引用

页码：85 / 87

页数：3

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