Palladium-Catalyzed Oxidative Cyclization for the Synthesis of Indolyl/Pyrrolyl 3-Phosphonates

被引：26
作者：
Mishra, Aniket [1 ]
Deb, Indubhusan [1 ]
机构：
[1] Indian Inst Chem Biol, Organ & Med Chem Div, 4 Raja SC Mullick Rd, Kolkata 700032, India
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2016年 / 358卷 / 14期
关键词：
C-H bond activation; imine-enamines; indoles; ketophosphonates; phosphonates; pyrroles; C-H ACTIVATION; N-ARYL ENAMINES; BOND FORMATION; INDOLE-DERIVATIVES; ARYLATION; FUNCTIONALIZATION; PHOSPHORYLATION; INHIBITORS; ANNULATION; AMINATION;
D O I：
10.1002/adsc.201600321
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Imino-/enaminophosphonates derived from amines and diethyl phenacyl phosphonates undergo oxidative cyclization via C-H bond activation catalyzed by palladium chloride to provide a convenient route for the synthesis of substituted indol-3-yl and pyrrol-3-yl phosphonates.
引用
收藏
页码：2267 / 2272
页数：6
相关论文
共 76 条
[1]   Phosphono-substituted isoindolines and indoles from 2,3-and 2,4-benzoxazin-1-ones [J].
Abdou, WM ;
Kamel, AA ;
Khidre, MD .
HETEROATOM CHEMISTRY, 2004, 15 (01) :77-84
[2]   General and efficient indole syntheses based on catalytic amination reactions [J].
Ackermann, L .
ORGANIC LETTERS, 2005, 7 (03) :439-442
[3]   Cationic Ruthenium(II) Catalysts for Oxidative C-H/N-H Bond Functionalizations of Anilines with Removable Directing Group: Synthesis of Indoles in Water [J].
Ackermann, Lutz ;
Lygin, Alexander V. .
ORGANIC LETTERS, 2012, 14 (03) :764-767
[4]   Domino Ligand-Free Copper-Catalyzed Synthesis of Polysubstituted Indoles [J].
Ali, Md Ashif ;
Punniyamurthy, Tharmalingam .
SYNLETT, 2011, (05) :623-626
[5]  
[Anonymous], 2009, ANGEW CHEM
[6]  
[Anonymous], 2009, ANGEW CHEM
[7]  
[Anonymous], 2014, Angew. Chem.
[8]  
[Anonymous], 2008, ANGEW CHEM
[9]   Copper-Catalyzed C-C Bond Formation through C-H Functionalization: Synthesis of Multisubstituted Indoles from N-Aryl Enaminones [J].
Bernini, Roberta ;
Fabrizi, Giancarlo ;
Sferrazza, Alessio ;
Cacchi, Sandro .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (43) :8078-8081
[10]   Update 1 of: Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions [J].
Cacchi, Sandro ;
Fabrizi, Giancarlo .
CHEMICAL REVIEWS, 2011, 111 :PR215-PR283
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