Advances in metal-assisted non-electrophilic fluoroalkylation reactions of organic compounds

被引：52

作者：

Lantano, Beatriz ^{[1
,2
]}

Torviso, M. Rosario ^{[1
]}

Bonesi, S. M. ^{[3
]}

Barata-Vallejo, S. ^{[1
]}

Postigo, Al ^{[1
]}

机构：

[1] Univ Buenos Aires, Fac Farm & Bioquim, Dept Quim Organ, RA-1113 Buenos Aires, DF, Argentina

[2] Univ Nacl Lujan, Dept Ciencias Basicas, Buenos Aires, DF, Argentina

[3] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Organ, RA-1428 Buenos Aires, DF, Argentina

来源：

COORDINATION CHEMISTRY REVIEWS | 2015年 / 285卷

关键词：

Metal-assisted trifluoromethylation; Fluoroalkylation of aromatics; Trifluoromethylation by metal-organic species; CROSS-COUPLING REACTIONS; COPPER-CATALYZED TRIFLUOROMETHYLATION; FLUOROFORM-DERIVED CUCF3; PD(II)-CATALYZED ORTHO-TRIFLUOROMETHYLATION; CU-MEDIATED TRIFLUOROMETHYLATION; ARYL BORONIC ACIDS; OXIDATIVE TRIFLUOROMETHYLATION; SANDMEYER TRIFLUOROMETHYLATION; RADICAL PERFLUOROALKYLATION; ARYLBORONIC ACIDS;

D O I：

10.1016/j.ccr.2014.11.004

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Metal-assisted trifluoromethylation and perfluoroalkylation reactions are probably one of the first approaches employed to achieve fluoroalkyl-group substitutions of organic substrates through the use of metals such as copper. Fluoroalkylation reactions of both aromatic and aliphatic substrates involving the employment of perfluoroalkyl halides RfX in conjunction with metallic species, and nucleophilic fluoroalkylating reagents in the presence of metals or organometallic species will be studied. Fluoroalkylation reactions utilizing electrophilic fluoroalkylating reagents in the presence of transition metals or trifluoromethylthiolation reactions will not be the subject of this article. Recently emerging literature (2011 present), with special emphasis on updates from previous review articles on the metal-mediated fluoroalkylation of aromatic substrates will be dealt with. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：76 / 108

页数：33

共 3 条

[1] Photocatalytic fluoroalkylation reactions of organic compounds
Barata-Vallejo, Sebastian
Bonesi, Sergio M.
Postigo, Al
ORGANIC & BIOMOLECULAR CHEMISTRY, 2015, 13 (46) : 11153 - 11183
[2] Advances in transition-metal catalyzed thioetherification reactions of aromatic compounds
Ghaderi, Arash
TETRAHEDRON, 2016, 72 (32) : 4758 - 4782
[3] Engineering Metal-Organic Framework Catalysts for C-C and C-X Coupling Reactions: Advances in Reticular Approaches from 2014-2018
Kousik, Shravan
Velmathi, Sivan
CHEMISTRY-A EUROPEAN JOURNAL, 2019, 25 (72) : 16451 - 16505

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