Cryptococcal breast abscess in an HIV-positive patient: Arguments for reviewing the definition of immune reconstitution inflammatory syndrome

被引：15

作者：

Haddow, Lewis J. ^{[1
,2
]}

Sahid, Faieza ^{[1
]}

Moosa, Mahomed-Yunus S. ^{[1
]}

机构：

[1] Univ KwaZulu Natl, Dept Infect Dis, Nelson R Mandela Sch Med, ZA-4013 Congella, South Africa

[2] Kings Coll London, Dept HIV & Genitourinary Med, London WC2R 2LS, England

来源：

JOURNAL OF INFECTION | 2008年 / 57卷 / 01期

基金：

英国医学研究理事会;

关键词：

Cryptococcus; HIV; breast; immune reconstitution; inflammatory syndrome;

D O I：

10.1016/j.jinf.2008.01.010

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Atypical manifestations of Cryptococcus neoformons disease have been reported in patients with HIV-1 infection as part of the spectrum of the immune reconstitution inflammatory syndrome (IRIS). We describe a cryptococcal breast abscess in a patient presenting after 11 months of highly active antiretroviral therapy (HAART). The arguments for and against the case being a novel manifestation of IRIS are discussed. The potential hazards of using CD4 count as a surrogate marker of IRIS and the danger of misdiagnosing IRIS as failure of HAART are highlighted. (c) 2008 The British Infection Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：82 / 84

页数：3

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