Transducer-based evaluation of tremor

被引：65

作者：

Haubenberger, Dietrich ^{[1
]}

Abbruzzese, Giovanni ^{[2
]}

Bain, Peter G. ^{[3
]}

Bajaj, Nin ^{[4
]}

Benito-Leon, Julian ^{[5
,6
,7
]}

Bhatia, Kailash P. ^{[8
]}

Deuschl, Guenther ^{[9
]}

Joao Forjaz, Maria ^{[10
,11
]}

Hallett, Mark ^{[12
]}

Louis, Elan D. ^{[13
,14
,15
]}

Lyons, Kelly E. ^{[16
]}

Mestre, Tiago A. ^{[17
]}

Raethjen, Jan ^{[9
]}

Stamelou, Maria ^{[18
,19
]}

Tan, Eng-King ^{[20
]}

Testa, Claudia M. ^{[21
]}

Elble, Rodger J. ^{[22
]}

机构：

[1] NINDS, Clin Trials Unit, Off Clin Director, NIH, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

[2] DINOGMI Univ Genoa, Genoa, Italy

[3] Imperial Coll London, Charing Cross Hosp, Dept Neurol, London, England

[4] Nottingham Univ Hosp NHS Trust, Dept Neurol, Nottingham, England

[5] Univ Hosp 12 Octubre, Dept Neurol, Madrid, Spain

[6] Ctr Invest Biomed Red Enfermedades Neurodegenerat, Madrid, Spain

[7] Univ Complutense, Dept Med, Madrid, Spain

[8] UCL, Inst Neurol, Sobell Dept Movement Neurosci, Queen Sq, London, England

[9] Univ Kiel, Dept Neurol, Kiel, Germany

[10] Carlos III Inst Hlth, Natl Sch Publ Hlth, Madrid, Spain

[11] Carlos III Inst Hlth, Red Invest Serv Sanitarios & Enfermedades Cron RE, Madrid, Spain

[12] NINDS, Human Motor Control Sect, NIH, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA

[13] Yale Sch Med, Dept Neurol, New Haven, CT USA

[14] Yale Sch Med, Dept Chron Dis Epidemiol, New Haven, CT USA

[15] Yale Univ, Yale Sch Publ Hlth, New Haven, CT USA

[16] Univ Kansas, Med Ctr, Kansas City, KS 66103 USA

[17] Univ Ottawa, Parkinsons Dis & Movement Disorders Ctr, Ottawa Brain & Mind Res Inst, Div Neurol,Dept Med,Ottawa Hosp,Res Inst, Ottawa, ON, Canada

[18] Univ Athens, Dept Dept, GR-10679 Athens, Greece

[19] Philipps Univ, Dept Neurol, Marburg, Germany

[20] Singapore Gen Hosp, Duke NUS Med Sch, Dept Neurol, Natl Inst Neurosci, SGH Campus, Singapore, Singapore

[21] Virginia Commonwealth Univ, Parkinsons & Movement Disorders Ctr, Richmond, VA USA

[22] Southern Illinois Univ, Sch Med, Dept Neurol, Springfield, IL USA

来源：

MOVEMENT DISORDERS | 2016年 / 31卷 / 09期

关键词：

tremor; transducers; accelerometry; electromyography; reproducibility of results; DEEP BRAIN-STIMULATION; TOXIN TYPE-A; BOTULINUM TOXIN; DOUBLE-BLIND; OPEN-LABEL; PHYSIOLOGICAL TREMOR; PARKINSONS-DISEASE; DIGITIZING TABLET; SPIRAL ANALYSIS; PROPRANOLOL;

D O I：

10.1002/mds.26671

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The International Parkinson and Movement Disorder Society established a task force on tremor that reviewed the use of transducer-based measures in the quantification and characterization of tremor. Studies of accelerometry, electromyography, activity monitoring, gyroscopy, digitizing tablet-based measures, vocal acoustic analysis, and several other transducer-based methods were identified by searching . The availability, use, acceptability, reliability, validity, and responsiveness were reviewed for each measure using the following criteria: (1) used in the assessment of tremor; (2) used in published studies by people other than the developers; and (3) adequate clinimetric testing. Accelerometry, gyroscopy, electromyography, and digitizing tablet-based measures fulfilled all three criteria. Compared to rating scales, transducers are far more sensitive to changes in tremor amplitude and frequency, but they do not appear to be more capable of detecting a change that exceeds random variability in tremor amplitude (minimum detectable change). The use of transducer-based measures requires careful attention to their limitations and validity in a particular clinical or research setting. (c) 2016 International Parkinson and Movement Disorder Society

引用

页码：1327 / 1336

页数：10

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