Review of treatment for discoid lupus erythematosus

被引：36
作者：
Garza-Mayers, Anna Cristina [1 ,2 ]
McClurkin, Michael [1 ]
Smith, Gideon P. [1 ,2 ]
机构：
[1] Harvard Med Sch, Boston, MA USA
[2] Massachusetts Gen Hosp, Dept Dermatol, Boston, MA 02114 USA
来源：
DERMATOLOGIC THERAPY | 2016年 / 29卷 / 04期
关键词：
discoid; lupus; chronic cutaneous; therapeutics; CUTANEOUS LUPUS; DOUBLE-BLIND; MYCOPHENOLATE-MOFETIL; CONTROLLED-TRIAL; EFFICACY; THERAPY; SMOKING; SAFETY; HYDROXYCHLOROQUINE; INFLAMMATION;
D O I：
10.1111/dth.12358
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Discoid lupus erythematosus (DLE) is a chronic cutaneous disease characterized by inflammatory plaques that, in the absence of prompt diagnosis and treatment, may lead to disfiguring scarring and skin atrophy. However, there is limited evidence for which treatments are most effective. Currently, no medications have been approved specifically for the treatment of DLE. Many of the drugs described in the literature were developed for use in other immune disorders. This review will summarize current therapeutic options for DLE and their supporting evidence with discussion of prevention, topical measures, physical modalities, and systemic therapies, including newer potential therapies.
引用
收藏
页码：274 / 283
页数：10
相关论文
共 50 条
[1]   Pimecrolimus 1% cream versus betamethasone 17-valerate 0.1% cream in the treatment of facial discoid lupus erythematosus: a double-blind, randomized pilot study [J].
Barikbin, B. ;
Givrad, S. ;
Yousefi, M. ;
Eskandari, F. .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2009, 34 (07) :776-780
[2]   Double-blind, randomized, controlled clinical trial of clofazimine compared with chloroquine in patients with systemic lupus erythematosus [J].
Bezerra, ELM ;
Vilar, MJP ;
Neto, PBD ;
Sato, EI .
ARTHRITIS AND RHEUMATISM, 2005, 52 (10) :3073-3078
[3]   Laser Therapy in the Treatment of Connective Tissue Diseases: A Review [J].
Brauer, Jeremy A. ;
Spratt, Elizabeth A. Gordon ;
Geronemus, Roy G. .
DERMATOLOGIC SURGERY, 2014, 40 (01) :1-13
[4]   AZATHIOPRINE - AN EFFECTIVE, CORTICOSTEROID-SPARING THERAPY FOR PATIENTS WITH RECALCITRANT CUTANEOUS LUPUS-ERYTHEMATOSUS OR WITH RECALCITRANT CUTANEOUS LEUKOCYTOCLASTIC VASCULITIS [J].
CALLEN, JP ;
SPENCER, LV ;
BURRUSS, JB ;
HOLTMAN, J .
ARCHIVES OF DERMATOLOGY, 1991, 127 (04) :515-522
[5]   SYSTEMIC LUPUS-ERYTHEMATOSUS - CLINICAL AND IMMUNOLOGICAL PATTERNS OF DISEASE EXPRESSION IN A COHORT OF 1,000 PATIENTS [J].
CERVERA, R ;
KHAMASHTA, MA ;
FONT, J ;
SEBASTIANI, GD ;
GIL, A ;
LAVILLA, P ;
DOMENECH, I ;
AYDINTUG, AO ;
JEDRYKAGORAL, A ;
DERAMON, E ;
GALEAZZI, M ;
HAGA, HJ ;
MATHIEU, A ;
HOUSSIAU, F ;
INGELMO, M ;
HUGHES, GRV ;
CERVERA, R ;
SEBASTIANI, GD ;
FONT, J ;
KHAMASHTA, MA ;
HUGHES, GRV ;
FONT, J ;
CERVERA, R ;
LOPEZSOTO, A ;
VIVANCOS, J ;
INGELMO, M ;
URBANOMARQUEZ, A ;
KHAMASHTA, MA ;
VIANNA, J ;
HUGHES, GRV ;
GIL, A ;
LAVILLA, P ;
PINTADO, V ;
LOPEZDUPLA, M ;
VAZQUEZ, JJ ;
SEBASTIANI, GD ;
DERAMON, E ;
CAMPS, M ;
FRUTOS, MA ;
PERELLO, I ;
SANTOS, PG ;
ABARCA, M ;
NEBRO, AF ;
DOMENECH, I ;
TOKGOZ, G ;
AYDINTUG, AO ;
JEDRYKAGORAL, A ;
MALDYKOWA, H ;
CHWALINSKASADOWSKA, H ;
GALEAZZI, M .
MEDICINE, 1993, 72 (02) :113-124
[6]   Response to Antimalarial Agents in Cutaneous Lupus Erythematosus [J].
Chang, Aileen Y. ;
Piette, Evan W. ;
Foering, Kristen P. ;
Tenhave, Thomas R. ;
Okawa, Joyce ;
Werth, Victoria P. .
ARCHIVES OF DERMATOLOGY, 2011, 147 (11) :1261-1267
[7]   Influence of smoking on the efficacy of antimalarials in cutaneous lupus: A meta-analysis of the literature [J].
Chasset, Francois ;
Frances, Camille ;
Barete, Stephane ;
Amoura, Zahir ;
Arnaud, Laurent .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2015, 72 (04) :634-639
[8]   Differential expression of BAFF and its receptors in discoid lupus erythematosus patients [J].
Chong, Benjamin F. ;
Tseng, Lin-chiang ;
Kim, Andrew ;
Miller, Rodney T. ;
Yancey, Kim B. ;
Hosler, Gregory A. .
JOURNAL OF DERMATOLOGICAL SCIENCE, 2014, 73 (03) :216-224
[9]   DAPSONE AND DISCOID LUPUS-ERYTHEMATOSUS [J].
COBURN, PR ;
SHUSTER, S .
BRITISH JOURNAL OF DERMATOLOGY, 1982, 106 (01) :105-106
[10]   Thalidomide in the treatment of refractory cutaneous lupus erythematosus: prognostic factors of clinical outcome [J].
Cortes-Hernandez, J. ;
Torres-Salido, M. ;
Castro-Marrero, J. ;
Vilardell-Tarres, M. ;
Ordi-Ros, J. .
BRITISH JOURNAL OF DERMATOLOGY, 2012, 166 (03) :616-623
12345