May the Force Be With You: Unfolding Lipid-Protein Interactions By Single-Molecule Force Spectroscopy

被引：1

作者：

Dowhan, William ^{[1
]}

Vitrac, Heidi ^{[1
]}

Bogdanov, Mikhail ^{[1
]}

机构：

[1] Univ Texas Houston, Sch Med, Dept Biochem & Mol Biol, Houston, TX 77030 USA

来源：

STRUCTURE | 2015年 / 23卷 / 04期

关键词：

MEMBRANE-PROTEIN; LACTOSE PERMEASE; ESCHERICHIA-COLI; DUAL TOPOLOGY;

D O I：

10.1016/j.str.2015.03.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this issue of Structure, Serdiuk et al. report the use of single-molecule force microscopy to establish a role for phosphatidylethanolamine in promoting the native fold of lactose permease, thereby preventing it from populating a functionally defective, nonnative conformation (Serdiuk et al., 2015).

引用

页码：612 / 614

页数：3

共 11 条

[1] PHOSPHATIDYLETHANOLAMINE IS REQUIRED FOR IN-VIVO FUNCTION OF THE MEMBRANE-ASSOCIATED LACTOSE PERMEASE OF ESCHERICHIA-COLI [J].

BOGDANOV, M ;

DOWHAN, W .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (02) :732-739

[2] Lipids and topological rules governing membrane protein assembly [J].

Bogdanov, Mikhail ;

Dowhan, William ;

Vitrac, Heidi .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2014, 1843 (08) :1475-1488

[3] Lipid-dependent Generation of Dual Topology for a Membrane Protein [J].

Bogdanov, Mikhail ;

Dowhan, William .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (45) :37939-37948

[4] Single-molecule studies of protein folding [J].

Borgia, Alessandro ;

Williams, Philip M. ;

Clarke, Jane .

ANNUAL REVIEW OF BIOCHEMISTRY, 2008, 77 :101-125

[5]

CHEN CC, 1984, J BIOL CHEM, V259, P150

[6] Structural determination of wild-type lactose permease [J].

Guan, Lan ;

Mirza, Osman ;

Verner, Gillian ;

Iwata, So ;

Kaback, H. Ronald .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (39) :15294-15298

[7] From valleys to ridges:: Exploring the dynamic energy landscape of single membrane proteins [J].

Janovjak, Harald ;

Sapra, K. Tanuj ;

Kedrov, Alexej ;

Mueller, Daniel J. .

CHEMPHYSCHEM, 2008, 9 (07) :954-966

[8] A chemiosmotic mechanism of symport [J].

Kaback, H. Ronald .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (05) :1259-1264

[9] FINE-TUNING THE TOPOLOGY OF A POLYTOPIC MEMBRANE-PROTEIN - ROLE OF POSITIVELY AND NEGATIVELY CHARGED AMINO-ACIDS [J].

NILSSON, IM ;

VONHEIJNE, G .

CELL, 1990, 62 (06) :1135-1141

[10] Observing a Lipid-Dependent Alteration in Single Lactose Permeases [J].

Serdiuk, Tetiana ;

Sugihara, Junichi ;

Mari, Stefania A. ;

Kaback, H. Ronald ;

Mueller, Daniel J. .

STRUCTURE, 2015, 23 (04) :754-761

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