Synthesis and biological evaluation of azetidinone derivatives with pyrazolone moiety

被引：0
|
作者：
Bhabhor, Falguni [1 ]
Dabhi, Harish [1 ]
机构：
[1] Navjivan Sci Coll, Dept Chem, Dahod 389151, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2021年 / 60卷 / 10期
关键词：
2-Azetidinone; pyrazolone; Schiff base; antimicrobial activity;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A Schiff base has been prepared by the reaction of 4-acetyl-5-methyl-2-(4-methylphenyl)-2,4-dihydro-3H-pyrazole-3-one with different substituted amines. Treatment of this Schiff base with chlorobactyl chloride affords the corresponding azetidinone in good yield. All the new compounds have been characterized by IR, H-1 NMR, GC -MS and elemental analysis. The antibacterial activity of these compounds has been determined with the reference of standard drug.
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收藏
页码：1396 / 1399
页数：4
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