Internal Morphological Effects of Growth Hormone Transgenesis in Coho Salmon

被引：1
作者：
Gaffney, L. P. [1 ]
Watson, B. M. [1 ]
Oakes, J. D. [1 ]
Devlin, R. H. [1 ]
机构：
[1] Fisheries & Oceans Canada, 4160 Marine Dr, W Vancouver, BC V7V 1H2, Canada
来源：
TRANSACTIONS OF THE AMERICAN FISHERIES SOCIETY | 2018年 / 147卷 / 06期
关键词：
ATLANTIC SALMON; RAINBOW-TROUT; PHOSPHORUS DEFICIENCY; GENE CONSTRUCT; SALAR L; FISH; PERFORMANCE; HOMEOSTASIS; PROTEIN; BRAIN;
D O I：
10.1002/tafs.10118
中图分类号：
S9 [水产、渔业];
学科分类号：
0908 ;
摘要：
Effects of growth hormone (GH) overexpression on internal morphology were examined in homozygous and hemizygous GH transgenic Coho Salmon Oncorhynchus kisutch aided by clearing and staining and magnetic resonance imaging methodologies. Morphological effects of transgenesis were observed in pin bones in fast-growing hemizygous transgenic salmon, in vertebral column and swim bladder deformities in homozygotes, and as nonproportional modifications to some cranial structures examined among groups. These data provide further examples of the complex pleiotropic effects arising from GH overexpression in transgenic salmon.
引用
收藏
页码：1199 / 1206
页数：8
相关论文
共 50 条
[31]   Gill Morphometry in Growth Hormone Transgenic Pacific Coho Salmon, Onchorhynchus kisutch, Differs Markedly from that in GH Transgenic Atlantic Salmon [J].
E. Don Stevens ;
Robert H. Devlin .
Environmental Biology of Fishes, 2000, 58 :113-117
[32]   Gill morphometry in growth hormone transgenic Pacific coho salmon, Onchorhynchus kisutch, differs markedly from that in GH transgenic Atlantic salmon [J].
Stevens, ED ;
Devlin, RH .
ENVIRONMENTAL BIOLOGY OF FISHES, 2000, 58 (01) :113-117
[33]   Acute cerebrovascular effects in juvenile coho salmon exposed to roadway runoff [J].
Blair, Stephanie, I ;
Barlow, Clyde H. ;
McIntyre, Jenifer K. .
CANADIAN JOURNAL OF FISHERIES AND AQUATIC SCIENCES, 2021, 78 (02) :103-109
[34]   Identification of ovarian genes regulated by follicle-stimulating hormone (Fsh) in vitro during early secondary oocyte growth in coho salmon [J].
Luckenbach, J. Adam ;
Yamamoto, Yoji ;
Guzman, Jose M. ;
Swanson, Penny .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2013, 366 (01) :38-52
[35]   Influence of dietary concentrations of protein, lipid and carbohydrate on growth, protein and energy utilization, body composition, and plasma titres of growth hormone and insulin-like growth factor-1 in non-transgenic and growth hormone transgenic coho salmon, Oncorhynchus kisutch (Walbaum) [J].
Higgs, D. A. ;
Sutton, J. N. ;
Kim, H. ;
Oakes, J. D. ;
Smith, J. ;
Biagi, C. ;
Rowshandeli, M. ;
Devlin, R. H. .
AQUACULTURE, 2009, 286 (1-2) :127-137
[36]   Effects of cortisol, growth hormone and prolactin on gill claudin expression in Atlantic salmon [J].
Tipsmark, C. K. ;
Jorgensen, C. ;
Brande-Lavridsen, N. ;
Engelund, M. ;
Olesen, J. H. ;
Madsen, S. S. .
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2009, 163 (03) :270-277
[37]   Propylthiouracil-induced hypothyroidism in coho salmon, Oncorhynchus kisutch: effects on plasma total thyroxine, total triiodothyronine, free thyroxine, and growth hormone [J].
L.O.E. Ebbesson ;
B. Th. Björnsson ;
S.O. Stefansson ;
P. Ekström .
Fish Physiology and Biochemistry, 1998, 19 :305-314
[38]   Propylthiouracil-induced hypothyroidism in coho salmon, Oncorhynchus kisutch:: Effects on plasma total thyroxine, total triiodothyronine, free thyroxine, and growth hormone [J].
Ebbesson, LOE ;
Björnsson, BT ;
Stefansson, SO ;
Ekström, P .
FISH PHYSIOLOGY AND BIOCHEMISTRY, 1998, 19 (04) :305-313
[39]   Fitness component assessments of wild-type and growth hormone transgenic coho salmon reared in seawater mesocosms [J].
Leggatt, Rosalind A. ;
Biagi, Carlo A. ;
Sakhrani, Dionne ;
Dominelli, Robert ;
Eliason, Erika J. ;
Farrell, Anthony P. ;
Devlin, Robert H. .
AQUACULTURE, 2017, 473 :31-42
[40]   Effects of fish meal- and fish oil-free diets on growth responses and fatty acid composition of juvenile coho salmon (Oncorhynchus kisutch) [J].
Twibell, Ronald G. ;
Gannam, Ann L. ;
Hyde, Nathan M. ;
Holmes, John S. A. ;
Poole, Jeff B. .
AQUACULTURE, 2012, 360 :69-77
12345