Syntheses of optically active 2-substituted cyclopropanecarboxylic acids from chiral α-hydroxysilane derivatives

被引：30

作者：

Sakaguchi, K ^{[1
]}

Mano, H ^{[1
]}

Ohfune, Y ^{[1
]}

机构：

[1] Osaka City Univ, Dept Mat Sci, Grad Sch Sci, Sumiyoshi Ku, Osaka 5588585, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 24期

关键词：

masked chirality; alpha-hydroxysilane; optically active cyclopropanecarboxylic acid; diastereoselective cyclopropanation;

D O I：

10.1016/S0040-4039(98)00759-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active 2-alkylcyclopropanecarboxylic acids were efficiently synthesized from the chiral alpha-hydroxytrimethylsilanes via a diastereoselective cyclopropanation as the key step, (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：4311 / 4312

页数：2

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