Immunoglobulin G crystalline keratopathy associated with monoclonal gammopathy

Purpose: Two cases of corneal crystal deposition are reported, both caused by a benign monoclonal gammopathy. Methods: Similar corneal pathology is identified in these two patients, both of whom presented with visual acuities of 6/6 or better: Consideration of possible causes involved biochemical and haematological testing and assessment. Results: Potential for malignant transformation of monoclonal gammopathy was recognized, hence the need for ongoing haematological follow-up. Conclusion: Corneal crystals may be the initial presentation in a patient with monoclonal gammopathy, a rare, but significant clinical finding.