Biomarkers for diagnosis of pre-eclampsia and endometriosis

被引:3
作者
Wahid, Braira [1 ,2 ]
Rafique, Shazia [3 ]
Ali, Amjad [2 ]
Waqar, Muhammad [1 ,2 ]
Nabi, Ghulam [4 ]
Wasim, Muhammad [5 ]
Idrees, Muhammad [1 ,2 ,3 ,5 ]
机构
[1] Al Sudais Plaza Abdalian Cooperat Soc, Genome Ctr Mol Based Diagnost & Res, Lahore, Pakistan
[2] Univ Punjab, CAMB, 87 West Canal Bank Rd Thokar Niaz Baig, Lahore, Pakistan
[3] Univ Punjab, CEMB, Div Mol Virol & Diagnost, 87 West Canal Bank Rd Thokar Niaz Baig, Lahore, Pakistan
[4] Chinese Acad Sci, Inst Hydrobiol, Wuhan, Hubei, Peoples R China
[5] Khyber Teaching Hosp, Dept Med, Peshawar, Pakistan
关键词
biomarkers; diagnosis; endometriosis; gynecological disorders; pre-eclampsia; ENDOTHELIAL GROWTH-FACTOR; OXIDATIVE STRESS MARKERS; PERITONEAL-FLUID; HYPERTENSIVE DISORDERS; POTENTIAL BIOMARKER; PROTEOMICS ANALYSIS; CIRCULATING LEVELS; SERUM MARKERS; KIDNEY INJURY; WOMEN;
D O I
10.2217/bmm-2018-0058
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Gynecological disorders are leading public health problems in developing countries with substantial impact on women's quality of life. Significant proportion of maternal mortality and reproductive morbidity is attributed to misdiagnosis andmismanagement of pregnancy related lethal pathological conditions and affect women's health. Timely diagnosis is necessary to prevent maternal deaths and to manage complications. Biomarker development will create a wide window of opportunity for early diagnosis. This review discusses the current status of biomarkers and recent advances in 'omics' technology for early screening of endometriosis and pre-eclampsia because of significant global bioburden associated with these disorders. This review will also give baseline data for future biomarker development strategies.
引用
收藏
页码:1161 / 1173
页数:13
相关论文
共 98 条
[1]   SURVIVIN AND VEGF AS NOVEL BIOMARKERS IN DIAGNOSIS OF ENDOMETRIOSIS [J].
Acimovic, Milena ;
Vidakovic, Snezana ;
Milic, Natasa ;
Jerernic, Katarina ;
Markovic, Milos ;
Milosevic-Djeric, Ana ;
Lazovic-Radonjic, Gordana .
JOURNAL OF MEDICAL BIOCHEMISTRY, 2016, 35 (01) :63-68
[2]   Biomarkers in endometriosis: challenges and opportunities [J].
Ahn, Soo Hyun ;
Singh, Vinay ;
Tayade, Chandrakant .
FERTILITY AND STERILITY, 2017, 107 (03) :523-532
[3]   ELEVATED SERUM LEVELS OF VASCULAR ENDOTHELIAL GROWTH-FACTOR IN PATIENTS WITH PREECLAMPSIA [J].
BAKER, PN ;
KRASNOW, J ;
ROBERTS, JM ;
YEO, KT .
OBSTETRICS AND GYNECOLOGY, 1995, 86 (05) :815-821
[4]   Prediction and prevention of recurrent preeclampsia [J].
Barton, John R. ;
Sibai, Baha M. .
OBSTETRICS AND GYNECOLOGY, 2008, 112 (02) :359-372
[5]   Relationship between nulliparity and preeclampsia may be explained by altered circulating soluble fms-like tyrosine kinase 1 [J].
Bdolah, Yuval ;
Elchalal, Uriel ;
Natanson-Yaron, Shira ;
Yechiam, Hadas ;
Bdolah-Abram, Tali ;
Greenfield, Caryn ;
Goldman-Wohl, Debra ;
Milwidsky, Ariel ;
Rana, Sarosh ;
Karumanchi, S. Ananth ;
Yagel, Simcha ;
Hochner-Celnikier, Drorith .
HYPERTENSION IN PREGNANCY, 2014, 33 (02) :250-259
[6]   SYNTHESIS OF ALPHA-1-ANTICHYMOTRYPSIN AND ALPHA-1-ANTITRYPSIN BY HUMAN TROPHOBLAST [J].
BERGMAN, D ;
KADNER, SS ;
CRUZ, MR ;
ESTERMAN, AL ;
TAHERY, MM ;
YOUNG, BK ;
FINLAY, TH .
PEDIATRIC RESEARCH, 1993, 34 (03) :312-317
[7]   Endometriosis is associated with a decreased risk of pre-eclampsia [J].
Brosens, Ivo A. ;
De Sutter, Petra ;
Hamerlynck, Tjalina ;
Imeraj, Lindita ;
Yao, Zhan ;
Cloke, Brianna ;
Brosens, Jan J. ;
Dhont, Marc .
HUMAN REPRODUCTION, 2007, 22 (06) :1725-1729
[8]   Proteomic profiling of urine identifies specific fragments of SERPINA1 and albumin as biomarkers of preeclampsia [J].
Buhimschi, Irina A. ;
Zhao, Guomao ;
Funai, Edmund F. ;
Harris, Nathan ;
Sasson, Isaac E. ;
Bernstein, Ira M. ;
Saade, George R. ;
Buhimschi, Catalin S. .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2008, 199 (05) :551.e1-551.e16
[9]   Novel Biomarkers for Predicting Preeclampsia [J].
Carty, David M. ;
Delles, Christian ;
Dominciczak, Anna F. .
TRENDS IN CARDIOVASCULAR MEDICINE, 2008, 18 (05) :186-194
[10]   Evidence supporting a rote for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia -: Young Investigator Award [J].
Chaiworapongsa, T ;
Romero, R ;
Espinoza, J ;
Bujoid, E ;
Kim, YM ;
Goçalves, LF ;
Gomez, R ;
Edwin, S .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2004, 190 (06) :1541-1547