Size controlled synthesis of well-distributed nano-silver on hydroxyapatite using alkanolamine compounds

被引：20

作者：

Labanni, Arniati ^{[1
]}

Zulhadjri ^{[1
]}

Handayani, Dian ^{[2
]}

Ohya, Yutaka ^{[3
]}

Arief, Syukri ^{[1
]}

机构：

[1] Andalas Univ, Fac Math & Sci, Dept Chem, Padang 25163, Indonesia

[2] Andalas Univ, Fac Pharm, Padang 25163, Indonesia

[3] Gifu Univ, Fac Engn, Dept Chem & Biomol Sci, Yanagido 1-1, Gifu 5011193, Japan

来源：

CERAMICS INTERNATIONAL | 2020年 / 46卷 / 05期

关键词：

Silver nanoparticle; Silver hydroxyapatite composite; Uncaria gambir Roxb; Bone implant; ANTIBACTERIAL PROPERTIES; NANOPARTICLES; NANOCOMPOSITE; COMPOSITES; RESISTANCE;

D O I：

10.1016/j.ceramint.2019.11.035

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

A well-distributed nano-silver hydroxyapatite composite has been successfully prepared by a one-pot synthesis method. Hydroxyapatite was separately synthesized by a sol-gel method, then impregnated with silver nanoparticles with the mediation of Uncaria gambir Roxb. leaf extract in the presence of three kinds of alkanolamine compound; monoethanolamine (MEA), diethanolamine (DEA), and triethanolamine (TEA) as capping agents. The effect of different capping agents on the properties of the silver nanoparticles and the nano-silver hydroxyapatite composite were studied. UV-visible spectrophotometer analysis exhibited absorbance peaks at 402-439 nm which specifically corresponds to spherical silver nanoparticles. Higher optical absorbance was observed in TEA-capped silver nanoparticles, than in DEA and MEA-capped ones. X-ray diffraction (XRD) analysis showed a highly crystalline hexagonal structure for hydroxyapatite and no detected metallic silver. However, the presence of 1.65% silver was confirmed by energy dispersive x-ray (EDX) spectroscopy analysis. Transmission electron microscopy (TEM) analysis revealed spherical silver nanoparticles with a size range of 2-62 nm (smallest mean diameter of 2 nm) adhered to the hydroxyapatite surface. The TEA capped impregnated silver nanoparticles were the smallest, corresponding to the best capping performance, followed by those capped by DEA and MEA. Small-sized nanoparticles on hydroxyapatite are beneficial for highly antibacterial bone implants.

引用

页码：5850 / 5855

页数：6

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