Room-Temperature Nickel-Catalysed Suzuki-Miyaura Reactions of Aryl Sulfonates/Halides with Arylboronic Acids

被引：65

作者：

Fan, Xin-Heng ^{[1
,2
]}

Yang, Lian-Ming ^{[1
]}

机构：

[1] Chinese Acad Sci, Beijing Natl Lab Mol Sci BNLMS, Inst Chem, New Mat Lab, Beijing 100190, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 2011卷 / 08期

基金：

中国国家自然科学基金;

关键词：

Cross-coupling; Nickel; Phosphane ligands; Halides; Boron; CROSS-COUPLING REACTIONS; EFFICIENT CATALYST; CHLOROARENES; ARENESULFONATES; MESYLATES; BIARYLS; CHLORIDES; HALIDES; ACTIVATION; AMINATION;

D O I：

10.1002/ejoc.201001519

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Room-temperature Suzuki-Miyaura aryl-aryl cross-coupling reactions have been achieved in high yields by using an easily accessible, air-stable Ni-II-(sigma-aryl) complex as precatalyst without either the pretreatment of organometallic reagents or the presence of external reductants. The Ni-II complex, in conjunction with monophosphane ligands such as PCy3 center dot HBF4 or PPh3, allowed the efficient cross-coupling of aryl sulfonates (OTs, OMs) and/or halides (Cl, Br, I) with arylboronic acids at room temperature in toluene/water in the presence of K2CO3 as base.

引用

页码：1467 / 1471

页数：5

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