Bile acid scaffolds in supramolecular chemistry: The interplay of design and synthesis

被引：80

作者：

Davis, Anthony P. ^{[1
]}

机构：

[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England

来源：

MOLECULES | 2007年 / 12卷 / 09期

关键词：

supramolecular chemistry; steroids; anion recognition; carbohydrate; recognition; stereoselective synthesis;

D O I：

10.3390/12082106

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Since early work in the 1980s, the bile acids have become well established as building blocks for supramolecular chemistry. The author's laboratory has specialised in converting cholic acid, the archetypal bile acid, into macrocyclic and acyclic receptors for anions and carbohydrates. This review highlights the synthetic aspects of this work, especially the use of modem synthetic methodology to perform less obvious structural transformations.

引用

页码：2106 / 2122

页数：17

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