Enantioselective separations by packed column subcritical and supercritical fluid chromatography

被引：49

作者：

Phinney, KW ^{[1
]}

机构：

[1] NIST, Div Analyt Chem, Chem Sci & Technol Lab, Gaithersburg, MD 20899 USA

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2005年 / 382卷 / 03期

关键词：

chiral separation; chiral stationary phase; enantiomers; method development; preparative; SFC;

D O I：

10.1007/s00216-005-3074-y

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Enantioselective separations have been one of the most successful applications of supercritical fluid chromatography (SFC). Although analytical scale separations have dominated the literature, the use of SFC for preparative chiral separations is growing. Both analytical and preparative scale SFC separations seek to take advantage of the high efficiency, high throughput, and rapid method development associated with the technique. This review will cover recent developments in the application of SFC to enantioseparations.

引用

页码：639 / 645

页数：7

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