Hyperthermia complicating tricyclic antidepressant overdose

被引：7
作者：
Hantson, P [1 ]
Benaissa, M [1 ]
Clemessy, JL [1 ]
Baud, FJ [1 ]
机构：
[1] HOP FERNAND WIDAL,PARIS,FRANCE
来源：
INTENSIVE CARE MEDICINE | 1996年 / 22卷 / 05期
关键词：
tricyclic antidepressants; overdose; hyperthermia;
D O I：
10.1007/BF01712165
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
We observed a 51-year-old woman who was admitted for severe amitriptyline overdose. Besides major cardiovascular complications, the patient developed severe hyperpyrexia with a central body temperature of more than 43 degrees C for 5 h. The patient died on day 3 from cardiocirculatory collapse and arrhythmias. Hyperthermia was unresponsive to cooling with ice water, gastric lavage, muscle relaxation, and dantrolene and bromocriptine administration. The possible mechanisms of refractory hyperthermia are discussed.
引用
收藏
页码：453 / 455
页数：3
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