Complete remission of ovarian small cell carcinoma treated with irinotecan and cisplatin: A case report

被引：1
作者：
Saitoh-Sekiguchi, Maki
Nakahara, Kenji
Kojimahara, Takanobu
Ohta, Tsuyoshi
Kawagoe, Jun
Ohnuki, Tsuyosi
Hayasaka, Tadashi
Motoyama, Teiichi
Kurachi, Hirohisa
机构：
[1] Yamagata Univ, Sch Med, Dept Obstet & Gynecol, Yamagata 9909585, Japan
[2] Yamagata Univ, Sch Med, Dept Pathol, Yamagata 9909585, Japan
来源：
ANTICANCER RESEARCH | 2007年 / 27卷 / 4C期
关键词：
ovary; small cell carcinoma; CPT-11; CDDP; irinotecan; cisplatin;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background: Small cell carcinoma of the ovary is a rare type of ovarian carcinoma with a very poor prognosis. Case Report: We report here a case of a 55-year-old woman with small cell carcinoma of the left ovary. The patient underwent cytoreductive surgery with residual tumors of 6 cm at the cul-de-sac and was found to have stage IIIc disease. After six courses of irinotecan (CPT-11) and cisplatin (CDDP) combination therapy, secondary cytoreductive surgery was performed. The patient showed no evidence of residual tumors. After an additional three courses of chemotherapy, the patient is still alive and well without evidence of disease. Conclusion: CPT-11 and CDDP combination chemotherapy may be effective and safe for patients with small cell carcinoma of the ovary.
引用
收藏
页码：2685 / 2687
页数：3
相关论文
共 13 条
[1]  
CLEMENT PB, 1991, SEMIN DIAGN PATHOL, V8, P204
[2]   PRIMARY OVARIAN SMALL-CELL CARCINOMA OF PULMONARY TYPE - A CLINICOPATHOLOGICAL, IMMUNOHISTOLOGIC, AND FLOW CYTOMETRIC ANALYSIS OF 11 CASES [J].
EICHHORN, JH ;
YOUNG, RH ;
SCULLY, RE .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1992, 16 (10) :926-938
[3]   Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer [J].
Kudoh, S ;
Fujiwara, Y ;
Takada, Y ;
Yamamoto, H ;
Kinoshita, A ;
Ariyoshi, Y ;
Furuse, K ;
Fukuoka, M ;
Takada, M ;
Ikegami, H ;
Nishikawa, H ;
Nakajima, S ;
Hoso, T ;
Higashino, K ;
Takahara, J ;
Kamei, M ;
Yamakido, M ;
Ryu, S ;
Hara, N ;
Fukuda, M ;
Kinuwaki, E ;
Tanaka, F ;
Senba, H ;
Araki, J .
JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (03) :1068-1074
[4]   A case of small cell carcinoma arising in a mature cystic teratoma of the ovary [J].
Lim, SC ;
Choi, SJ ;
Suh, CH .
PATHOLOGY INTERNATIONAL, 1998, 48 (10) :834-839
[5]  
LO RG, 1994, ANN ONCOL, V5, P909
[6]   CPT-11 - A NEW DERIVATIVE OF CAMPTOTHECIN FOR THE TREATMENT OF REFRACTORY OR RELAPSED SMALL-CELL LUNG-CANCER [J].
MASUDA, N ;
FUKUOKA, M ;
KUSUNOKI, Y ;
MATSUI, K ;
TAKIFUJI, N ;
KUDOH, S ;
NEGORO, S ;
NISHIOKA, M ;
NAKAGAWA, K ;
TAKADA, M .
JOURNAL OF CLINICAL ONCOLOGY, 1992, 10 (08) :1225-1229
[7]  
Mebis J, 2004, EUR J GYNAECOL ONCOL, V25, P239
[8]   Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer [J].
Noda, W ;
Nishiwaki, Y ;
Kawahara, M ;
Negoro, S ;
Sugiura, T ;
Yokoyama, A ;
Fukuoka, M ;
Mori, K ;
Watanabe, K ;
Tamura, T ;
Yamamoto, S ;
Saijo, N .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (02) :85-91
[9]   PRIMARY OVARIAN SMALL-CELL CARCINOMA - 4 MORE CASES [J].
PECCATORI, F ;
BONAZZI, C ;
LUCCHINI, V ;
BRATINA, G ;
MANGIONI, C .
GYNECOLOGIC ONCOLOGY, 1993, 49 (01) :95-99
[10]   SMALL-CELL CARCINOMA OF THE OVARY WITH HYPERCALCEMIA - REPORT OF A CASE OF SURVIVAL WITHOUT RECURRENCE 5 YEARS AFTER SURGERY AND CHEMOTHERAPY [J].
REED, WC .
GYNECOLOGIC ONCOLOGY, 1995, 56 (03) :452-455
12