N-heterocyclic carbene-catalyzed cyclocondensation of 2-aryl carboxylic acids and enones: highly enantioselective synthesis of δ-lactones

被引：23
作者：
Cheng, Jin-Tang [1 ]
Chen, Xiang-Yu [1 ]
Ye, Song [1 ,2 ]
机构：
[1] Chinese Acad Sci, Key Lab Mol Recognit & Funct, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
[2] Jiangxi Normal Univ, Natl Engn Res Ctr Carbohydrate Synth, Nanchang 330022, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2015年 / 13卷 / 05期
基金：
美国国家科学基金会;
关键词：
DIELS-ALDER REACTIONS; TRICYCLIC-BETA-LACTONES; ASYMMETRIC-SYNTHESIS; TRIFLUOROMETHYL DIHYDROPYRANONES; DISUBSTITUTED KETENES; ENOLATE EQUIVALENTS; ALDOL-LACTONIZATION; 4+2 CYCLOADDITION; KETO ACIDS; DERIVATIVES;
D O I：
10.1039/c4ob02330g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The enantioselective N-heterocyclic carbene-catalyzed [4 + 2] cyclocondensation of 2-aryl carboxylic acids and enones was developed, affording the corresponding chiral delta-lactones in good yields with good diastereo- and high enantioselectivities.
引用
收藏
页码：1313 / 1316
页数：4
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