Visualizing the Heterogeneity of Retinal Microglia

被引：7

作者：

Lin, Jonathan B. ^{[1
]}

Apte, Rajendra S. ^{[1
,2
,3
]}

机构：

[1] Washington Univ, Sch Med, Dept Ophthalmol & Visual Sci, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Dept Med, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Dept Dev Biol, St Louis, MO 63130 USA

来源：

IMMUNITY | 2019年 / 50卷 / 03期

关键词：

PHOTORECEPTOR DEGENERATION; PHAGOCYTOSIS; ACTIVATION; FATE;

D O I：

10.1016/j.immuni.2019.02.017

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In this issue of Immunity, O'Koren et al. (2019) report that murine retinal microglia are long lived and are divided into two spatially and functionally distinct niches in the retina. In models of retinal neurodegeneration, retinal microglia migrate to the subretinal space, an inducible disease-associated niche, where they are neuroprotective.

引用

页码：544 / 546

页数：4

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