Entomoculture: A Preliminary Techno-Economic Assessment

被引:6
作者
Ashizawa, Reina [1 ]
Rubio, Natalie [2 ]
Letcher, Sophia [2 ]
Parkinson, Avery [2 ]
Dmitruczyk, Victoria [3 ]
Kaplan, David L. [2 ]
机构
[1] Tufts Univ, Dept Biol, Medford, MA 02155 USA
[2] Tufts Univ, Dept Biomed Engn, Medford, MA 02155 USA
[3] McMaster Univ, Sch Life Sci, Hamilton, ON L8S 4L8, Canada
关键词
cultured meat; cell-based meat; technoeconomic assessment; insect cells; RECOMBINANT PROTEIN-PRODUCTION; OXYGEN-UPTAKE RATE; RABIES VIRUS GLYCOPROTEIN; SCHNEIDER; CELLS; SERUM-FREE MEDIUM; INSECT CELLS; SPODOPTERA-FRUGIPERDA; PERFUSION CULTURE; FREE MEDIA; S2;
D O I
10.3390/foods11193037
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Cultured meat, or the practice of growing meat from cell culture, has been experiencing rapid advances in research and technology as the field of biotechnology attempts to answer the call to fight climate change and feed a growing global population. A major hurdle for cell-based meat products entering the market in the near-future is their price. The complex production facilities required to make such products will require advanced bioreactor systems, resources such as energy and water, and a skilled labor force, among other factors. The use of insect cells in this process is hypothesized to address some of these costs due to the characteristics that make them more resilient in cell culture when compared to traditional livestock-derived cells. To address the potential for cost savings by utilizing insect cells in the cultivation of protein-enriched foods, here we utilized a techno-economic assessment model. Three different insect cell lines were used in the model. The results indicate that insect cell lines offer potential to significantly reduce the cost per kilogram of cell cultivated meat, along with further opportunities to optimize production processes through technological advances and scaling.
引用
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页数:21
相关论文
共 71 条
[1]  
Allan R. P., 2021, IPCC, 2021: Summary for Policymakers
[2]  
[Anonymous], FAQS UPSIDE FOODS
[3]  
ARCHAMBAULT J, 1994, BIOPROCESS ENG, V11, P189, DOI 10.1007/BF00369629
[4]  
Broucek J., 2014, Journal of Environmental Protection, V5, P1482, DOI 10.4236/jep.2014.515141
[5]   Drosophila imaginal disc growth factor 2 is a trophic factor involved in energy balance, detoxification, and innate immunity [J].
Broz, Vaclav ;
Kucerova, Lucie ;
Rouhova, Lenka ;
Fleischmannova, Jana ;
Strnad, Hynek ;
Bryant, Peter J. ;
Zurovec, Michal .
SCIENTIFIC REPORTS, 2017, 7
[6]   HIGH-LEVEL RECOMBINANT PROTEIN-PRODUCTION IN BIOREACTORS USING THE BACULOVIRUS INSECT CELL EXPRESSION SYSTEM [J].
CARON, AW ;
ARCHAMBAULT, J ;
MASSIE, B .
BIOTECHNOLOGY AND BIOENGINEERING, 1990, 36 (11) :1133-1140
[7]  
Chan LCL, 2016, METHODS MOL BIOL, V1350, P161, DOI 10.1007/978-1-4939-3043-2_8
[8]   High density culture of insect cells using rational medium design and feeding strategy [J].
Chiou, TW ;
Hsieh, YC ;
Ho, CS .
BIOPROCESS ENGINEERING, 2000, 22 (06) :483-491
[9]   Possibilities for an in vitro meat production system [J].
Datar, I. ;
Betti, M. .
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES, 2010, 11 (01) :13-22
[10]   OPTIMIZATION OF THE GROWTH-CONDITIONS OF SF21 INSECT CELLS FOR HIGH-DENSITY PERFUSION CULTURE IN STIRRED-TANK BIOREACTORS [J].
DEUTSCHMANN, SM ;
JAGER, V .
ENZYME AND MICROBIAL TECHNOLOGY, 1994, 16 (06) :506-512