Modifying Fe3O4-Functionalized Nanoparticles with N-Halamine and Their Magnetic/Antibacterial Properties

被引：138

作者：

Dong, Alideertu ^{[1
,2
]}

Lan, Shi ^{[3
]}

Huang, Jinfeng ^{[4
]}

Wang, Tao ^{[1
,2
]}

Zhao, Tianyi ^{[1
,2
]}

Xiao, Linghan ^{[1
,2
]}

Wang, Weiwei ^{[1
,2
]}

Zheng, Xin ^{[1
,2
]}

Liu, Fengqi ^{[1
,2
]}

Gao, Ge ^{[1
,2
]}

Chen, Yuxin ^{[4
]}

机构：

[1] Jilin Univ, Coll Chem, Changchun 130021, Peoples R China

[2] MacDiarmid Lab, Changchun 130021, Peoples R China

[3] Inner Mongolia Univ Nationalities, Coll Chem & Chem Engn, Tongliao 028000, Peoples R China

[4] Jilin Univ, Key Lab Mol Enzymol & Engn, Minist Educ, Changchun 130012, Peoples R China

来源：

ACS APPLIED MATERIALS & INTERFACES | 2011年 / 3卷 / 11期

基金：

中国国家自然科学基金;

关键词：

N-halamine; SiO2; Fe3O4; poly(styrene-co-acrylate acid); nanoparticles; bifunctional; QUATERNARY AMMONIUM; ANTIBACTERIAL ACTIVITY; BIOLOGICAL-ACTIVITY; POLYMERIC BIOCIDES; CHLORINE; SPHERES; WATER; MICROSPHERES; IMMOBILIZATION; NANOCOMPOSITES;

D O I：

10.1021/am200864p

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Magnetic/antibacterial bifunctional nanoparticles were fabricated through the immobilization of antibacterial N-halamine on silica-coated Fe3O4-decorated poly(styrene-co-acrylate acid) (PSA) nanoparticles. The samples were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectra (XPS), X-ray diffraction (XRD), energy-dispersive X-ray spectrometry (EDX), Fourier transform infrared (FTIR), and thermogravimetric analysis (TGA). The N-halamine was developed from the precursor 5,5-dimethylhydantoin (DMH) by chlorination treatment, and experimental results showed that the loading amount of DMH on the silica-coated Fe3O4-decorated poly(styrene-co-acrylate acid) nanoparticles was adjustable. The as-synthesized nanoparticles exhibited superparamagnetic behavior and had a saturation magnetization of 1893 emu g(-1). Antibacterial tests showed that the resultant nanoparticles displayed enhanced antibacterial activity against both Gram-positive and Gram-negative bacteria compared with their bulk counterparts.

引用

页码：4228 / 4235

页数：8

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