Food reward system: current perspectives and future research needs

被引：155

作者：

Alonso-Alonso, Miguel ^{[1
]}

Woods, Stephen C. ^{[2
]}

Pelchat, Marcia ^{[3
]}

Grigson, Patricia Sue ^{[4
]}

Stice, Eric ^{[5
]}

Farooqi, Sadaf ^{[6
]}

Khoo, Chor San ^{[7
]}

Mattes, Richard D. ^{[8
]}

Beauchamp, Gary K. ^{[3
]}

机构：

[1] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Ctr Study Nutr Med, Boston, MA 02215 USA

[2] Univ Cincinnati, Dept Psychiat & Behav Neurosci, Cincinnati, OH USA

[3] Monell Chem Senses Ctr, Philadelphia, PA 19104 USA

[4] Penn State Coll Med, Dept Neural & Behav Sci, Hershey, PA USA

[5] Univ Texas Austin, Dept Psychol, Austin, TX 78712 USA

[6] Univ Cambridge, Wellcome Trust MRC Inst Metab Sci, Cambridge, England

[7] Int Life Sci Inst, Amer Branch, Washington, DC 20005 USA

[8] Purdue Univ, Dept Nutr Sci, W Lafayette, IN 47907 USA

来源：

NUTRITION REVIEWS | 2015年 / 73卷 / 05期

关键词：

addiction; craving; definitions; food reward system; palatable food; translational science; REDUCED STRIATAL RESPONSE; INDUCED DOPAMINE RELEASE; BODY-MASS INDEX; WEIGHT-GAIN; ACCUMBENS DOPAMINE; NUCLEUS-ACCUMBENS; BRAIN ACTIVITY; SMOKING OPPORTUNITY; EATING-DISORDERS; D2; RECEPTORS;

D O I：

10.1093/nutrit/nuv002

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

This article reviews current research and cross-disciplinary perspectives on the neuroscience of food reward in animals and humans, examines the scientific hypothesis of food addiction, discusses methodological and terminology challenges, and identifies knowledge gaps and future research needs. Topics addressed herein include the role of reward and hedonic aspects in the regulation of food intake, neuroanatomy and neurobiology of the reward system in animals and humans, responsivity of the brain reward system to palatable foods and drugs, translation of craving versus addiction, and cognitive control of food reward. The content is based on a workshop held in 2013 by the North American Branch of the International Life Sciences Institute.

引用

页码：296 / 307

页数：12

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