Cardiovascular abnormalities in ageing and in uraemia - only analogy or shared pathomechanisms?

被引：22

作者：

Amann, K

Ritz, E

机构：

[1] Heidelberg Univ, Dept Internal Med, D-69115 Heidelberg, Germany

[2] Heidelberg Univ, Dept Pathol, D-69115 Heidelberg, Germany

来源：

NEPHROLOGY DIALYSIS TRANSPLANTATION | 1998年 / 13卷

关键词：

D O I：

10.1093/ndt/13.suppl_7.6

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

The analogies between the effects of ageing and of uraemia on the function and the structure of central elastic arteries and of the heart are striking. Qualitatively similar changes are seen in pulse contour, pulse wave velocity, and impedance and also similar structural abnormalities with wall thickening, diminished elastin, and increased collagen content. The altered 'Windkessel' function of central arteries in age and uraemia is one factor contributing to left ventricular hypertrophy.

引用

页码：6 / 11

页数：6

共 27 条

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[2] Aortic changes in experimental renal failure - Hyperplasia or hypertrophy of smooth muscle cells? [J].