Phenolics from the Fruits of Maclura pomifera

被引：0

作者：

Su, Zushang ^{[1
]}

Wang, Ping ^{[1
]}

Yuan, Wei ^{[1
]}

Grant, Greg ^{[2
]}

Li, Shiyou ^{[1
]}

机构：

[1] Stephen F Austin State Univ, Natl Ctr Pharmaceut Crops, Arthur Temple Coll Forestry & Agr, Nacogdoches, TX 75962 USA

[2] Stephen F Austin State Univ, Pineywoods Native Plant Ctr, Arthur Temple Coll Forestry & Agr, Nacogdoches, TX 75962 USA

来源：

NATURAL PRODUCT COMMUNICATIONS | 2017年 / 12卷 / 11期

关键词：

Maclura pomifera; Osage orange; Moraceae; Bishomoflavone; 2-Arylbenzofuran; Cytotoxicity; OSAGE ORANGE; FLAVONOIDS; COMPONENTS; ESTERS;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new compounds, maclurin A (1) and maclurin B (2), and six known ones, ononin (3), pterofuran (4), osajin (5), pomiferin (6), 3,4-dihydroxybenzoic acid (7), and 2,3,4-trihydroxybenzoic acid (8) were isolated from the fruit of Madura pomifera. Compounds 3 and 4 were isolated from the genus for the first time. Structure elucidation was achieved by spectroscopic measurements and by comparison with literature data. Compounds 2-4 exhibited activities against the cancer cell lines A549 and Panc-28 with GI(50) values from 18.1 to 32.2, and 20.6 to 43.5 mu M, respectively. Compounds 2 and 4 also showed cytotoxicity against HCT 116 with GI(50) values of 47.2 and 24.4 mu M, respectively.

引用

页码：1743 / 1745

页数：3

共 20 条

[1] INTERACTION OF SALMONELLA-TELAVIV WITH MACLURA-POMIFERA LECTIN [J].