Ophthalmia neonatorum: what kind of prophylaxis?

被引:33
|
作者
Zuppa, Antonio Alberto [1 ]
D'Andrea, Vito [1 ]
Catenazzi, Piero [1 ]
Scorrano, Antonio [1 ]
Romagnoli, Costantino [1 ]
机构
[1] Univ Cattolica Sacro Cuore, Div Neonatol, Dept Pediat, I-00168 Rome, Italy
来源
关键词
Newborn; conjunctivitis; pharmacotherapy; SILVER-NITRATE; CHLAMYDIA-TRACHOMATIS; NEISSERIA-GONORRHOEAE; POVIDONE-IODINE; EYE DROPS; CONJUNCTIVITIS; ERYTHROMYCIN; PREVENTION; TETRACYCLINE; CHLORAMPHENICOL;
D O I
10.3109/14767058.2010.531326
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Methods. aEuro integral Topical ocular prophylaxis must be instituted early after birth. Recommended prophylactic regimen are: 1%% nitrate solution; 1%% tetracycline solution; 1%% erythromycin solution; 2.5%% povidone-iodine solution; and fusidic acid. Results. aEuro integral Evidence suggests better outcomes using 1%% tetracycline solutions even if there is the risk of selecting drug resistant bacteria. However, even the widespread used nitrate solution can cause a chemical conjunctivitis, arguing against its widespread use. Conclusions. aEuro integral Fusidic acid is a relatively new promising therapy even if there are still few data about its use. None of the used regimens has the optimal risk-benefit profile to suggest a widespread use.
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页码:769 / 773
页数:5
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