Facile synthesis of some new fluorine containing spiro [3H-indole-3,2′tetrahydro-1,3-thiazine].2,4′(1H)-diones

被引：5

作者：

Dandia, A ^{[1
]}

Sharma, CS ^{[1
]}

Saha, M ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1998年 / 139卷

关键词：

fluorinated indole-2,3-diones; fluorinated spiro[indole-thiazine; 3-mercaptopropanoic acid; spectral studies;

D O I：

10.1080/10426509808035677

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Attempts have been made to synthesize exclusively 5',b'-dihydro-spiro [3H-indol-3,2'-[2H-1,3] thiazine]-2,4'(1H.3'H)-diones (V) under varying reaction conditions such as temperature, reaction period and molar ratio of the two reactants, by the reaction of fluorinated indole-2,3-diones (I) with fluorinated anilines (II) and 3-mercaptopropanoic acid (IV). The reaction of 3-indolylimines (III) with a slight excess of IV at room temperature, resulted in the formation of an acidic compound (VI), instead of expected spiro product (V), which has been further subjected to acetylation and chloroacetylation. The compounds have been characterized on the basis of elemental and spectral studies.

引用

页码：57 / 66

页数：10