One-pot synthesis of α-trifluoromethylstyrenes from aryl ketones and the Ruppert-Prakash reagent

被引：5

作者：

Levin, Vitalij V. ^{[1
]}

Dilman, Alexander D. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Moscow 119991, Russia

来源：

MENDELEEV COMMUNICATIONS | 2021年 / 31卷 / 05期

基金：

俄罗斯科学基金会;

关键词：

organofluorine compounds; trifluoromethylation; silicon reagents; ketones; alkenes; GEM-DIFLUOROALKENES; ALCOHOLS; ANION; CF3;

D O I：

10.1016/j.mencom.2021.09.030

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new synthesis of alpha-trifluoromethylstyrenes from aromatic ketones and (trifluoromethyl)trimethylsilane is described. The reaction involves nucleophilic trifluoromethylation and elimination of trimethylsilanol, which are performed within one reaction flask.

引用

页码：684 / 685

页数：2

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